Graduate Training in Molecular Biology and Biophysics

7.项目总结/摘要 此申请是为了更新俄勒冈州的长期存在的分子生物学& 生物物理学研究生训练计划。我们的目标是培养下一代严谨，创新， 以及实验技术熟练的分子生物学家和生物药理学家。我们的学员培养领导研究的技能 他们自己的程序，交流发现，以其他科学家和外行公众，并教导未来 几代科学家。在许多活跃而多样化的实验室之一进行个性化的研究培训， 我们计划的核心。学员可以通过聘请联合顾问来整合培训来增强这种体验 从两个组。本次培训活动以分子生物学研究所为中心， 具有相关科学兴趣的其他团体。资金要求12个博士前职位，在一个 该计划包括68名研究生，42名博士后研究员和26名培训教师， 部门在过去的资助周期中，我们增加了生物物理学领域的培训人员数量 （Guenza，Harms，Prell和Ursell），并增加了其他四个新的教师，涵盖了该计划的不同主题。 这些新的培训教员中的每一个都与培训的其他成员广泛合作 教师。培训学院的实验室是连续的，并在相互连接的建筑物， 促进教师和学生之间强有力的跨学科互动和合作。 培训的基本方面是在教员指导下进行的实验室研究 分子生物学和生物物理学培训项目通过这种体验，学员成为 擅长提出有关基本生物过程的问题，并设计实验来回答这些问题。 问题.培训得到了正规课程的加强，这些课程涵盖核心分子生物学、生物化学和生物化学。 生物物理领域以及计算、统计、定量培训和研究的道德行为。的 论文咨询委员会（每年至少召开一次会议）的积极参与确保了积极的 辅导和指导，以及评估受训人员的个人发展计划和进展， 计划的目标，因为受训者通过该计划的进展。我们围绕实验室和课程作业， 丰富的提升和拓展经验。例子包括第一年的轮换，教学，一个积极的 论文咨询委员会，期刊俱乐部，年度学生研究研讨会，以及与来访者的互动 扬声器.我们提供了几个新的职业发展活动，以支持学生有兴趣 每年有5-10名客座演讲者。学员通过以下方式成为经验丰富的演讲者： 定期期刊俱乐部介绍和他们的年度计划范围内的研究生研究研讨会开始， 训练的第三年。培训设施包括教师的实验室和广泛的服务 如结构生物学生物物理设施，最先进的基因组学和成像设施，以及 大量的其他现代化的共享设施。主要设备是共用的，存放在共用空间。

7. PROJECT SUMMARY/ABSTRACT This application is to renew funding of the University of Oregon's long-standing Molecular Biology & Biophysics graduate training program. Our goal is to train leaders of the next generation of rigorous, innovative, and experimentally-skilled molecular biologists and biophysicists. Our trainees develop the skills to lead research programs of their own, communicate discoveries to other scientists and the lay public, and teach future generations of scientists. Individualized research training within one of many active and diverse laboratories is the core of our program. Trainees may enhance this experience by engaging co-advisors to integrate training from two groups. This training activity is centered in the Institute of Molecular Biology, and also involves additional groups with related scientific interests. Funds are requested for 12 predoctoral positions, within a program that includes 68 graduate students, 42 postdoctoral fellows, and 26 training faculty across three departments. During the past funding cycle, we expanded the number of trainers in the biophysics area (Guenza, Harms, Prell and Ursell), and added four other new faculty covering diverse topics in the program. Each of these new training faculty members collaborates extensively with other members of the training faculty. The laboratories of the training faculty are contiguous and in interconnected buildings, an arrangement that fosters strong interdisciplinary interactions and collaborations among faculty and students. The basic aspect of the training is laboratory research carried out under the direction of a faculty member in the molecular biology and biophysics training program. Through this experience, the trainee becomes skilled at posing questions about fundamental biological processes and designing experiments to answer those questions. The training is augmented by formal courses that cover core molecular biology, biochemistry and biophysics areas, as well computing, statistics, quantitative training and the ethical conduct of research. The very active involvement of the Thesis Advisory Committee (meeting at least once per year) ensures active mentoring and guidance, as well as assessment of trainee individual development plans and progress towards the goals of the plan as trainees progress through the program. We surround the lab and coursework with a wealth of enhancing and broadening experiences. Examples include first-year rotations, teaching, an active thesis advisory committee, journal clubs, annual student research seminars, and interactions with visiting speakers. We provide several newly enhanced career developmental activities to support students interested in non-academic careers with 5-10 visiting speakers per year. Trainees become experienced speakers through regular journal club presentations and by their annual program-wide graduate research seminars beginning in their third year of training. The training facilities include the laboratories of the faculty and extensive services such as the structural biology biophysical facility, the state-of-the-art genomics and imaging facilities, and a large number of other modern shared facilities. Major equipment is shared and housed in common space.