Topic 375: Novel Diagnostic Imaging Modality for Monitoring Tumor Responses to a Hyperthermia Immunotherapy (Moonshot)
Topic 375: Novel Diagnostic Imaging Modality for Monitoring Tumor Responses to a Hyperthermia Immunotherapy (Moonshot)
批准号:
9786928
负责人:
Thomas E. Ramsay
金额:
$29.97万
依托单位:
--
依托单位国家:
美国
项目类别:
财政年份:
2018
资助国家:
美国
项目状态:
已结题
起止时间:
2018-09-14 至 2019-06-16
关键词:
AffectAlgorithmsBreast Cancer ModelComplexComputer softwareContractsDiagnosticDiagnostic ImagingDiagnostic radiologic examinationHyperthermiaImageImmune systemImmunotherapyMonitorPatient MonitoringPatientsPhaseResearchSystemTissue SampleTreatment Efficacybasecancer immunotherapycancer therapyexperienceimage processingimaging modalityimaging softwareinnovationmicroscopic imagingmouse modelnovel diagnosticsoutcome forecastresponsetumortumor microenvironment
中文摘要
在过去的几十年里,免疫疗法已经成为治疗癌症的有力方法。然而,免疫系统是复杂的,治疗效果很大程度上受肿瘤微环境的影响。因此,目前很难可视化肿瘤反应和预测治疗效果。
英文摘要
Immunotherapies have been emerging in the past decades as powerful approaches for cancer treatment. However, the immune system is complex, and therapy efficacy is substantially affected by the tumor microenvironment. For this reason, it is currently difficult to visualize tumor response and predict therapeutic efficacy.
In this Contract, Imago Systems, Inc., a company with substantial experience in breakthrough software-based diagnostic imaging, will collaborate with Kaio Therapy (innovative hyperthermia platform for cancer immunotherapy) to marry powerful, innovative diagnostic image processing algorithms and hyperthermia immunotherapy.
In the long term, this research is expected to provide a unique solution for a comprehensive and innovative diagnostic approach capable of evaluating efficacy of the treatment, monitoring patients' prognosis, and identifying patients who are likely to respond to the immunotherapy.
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