Boston University Clinical and Translational Science Institute

摘要 1.受资助父母补助金汇总表(BU CTSI) 波士顿大学临床与转化科学研究所(BU CTSI)的总体主题是 探索和解决翻译科学中的主要挑战，特别是那些解决特殊问题的挑战 城市高危社区弱势人群的健康问题 部署新的工具、方法和流程以加快我们中心的临床研究并将其国有化 与CTSA网络共享独特的资源。为此，我们将发挥我们在发展中的优势 跨不同项目的多学科、多文化协作团队。这种方法在BU上沿用 CTSI在自己的中心内积极参与与其他CTSA的持续和有力对话的历史 中心，并与NCATS一起寻找机会，在当地和 全国范围内。我们的目标是： 目标1.发现、演示、部署和传播新的计划，以开发我们的 科学工作者。 目标2.进一步加强我们强大的翻译科学环境，以鼓励翻译的各个方面 研究，从科学发现到高效的临床研究企业，发挥我们在基础研究方面的优势 和临床科学，通过这样做，解决了我们的高危患者的健康差距，并使 从我们的合作伙伴和附属机构那里吸取的经验教训和开发的资源可供CTSA网络使用。 目标3.在我们的所有社区利益相关者(患者、 供应商、采购商、付款人、公共政策制定者/倡导者、产品制定者和主要调查人员)以 在我们特殊人群的整个生命周期内加强协作翻译研究，并支持 在我们的ACO中，将研究整合到卫生保健中的方法。 目标4.与CTSA其他中心合作，发现、开发和传播创新的工具、方法 以及改善治疗和诊断研究的计划，以解决我们当地和全国的健康问题 有问题。 目标5.开发和演示新的信息学创新，以改进本地中心的翻译研究 我们独特的学习卫生系统，并将这些创新传播到CTSA网络。 BU CTSI的愿景是成为翻译研究的最强有力的倡导者和参与者， 通过支持我们的社区和社区，满足我们各种高危URG患者的健康需求 创建可与国家CTSA网络整合并分发给国家CTSA网络的独特资源。

SUMMARY 1. Summary of the funded parent grant (BU CTSI) The overall theme of the Boston University Clinical and Translational Science Institute (BU CTSI) is to explore and solve major challenges in translational science, especially those that address the special health problems of disadvantage individuals from urban at risk communities by developing and deploying new tools, methods and processes to expedite clinical research in our hub and nationalize shared unique resources with the CTSA Network. To do this we will exploit our strengths in developing multi-disciplinary, multi-cultural collaborative teams across diverse programs. This approach follows on the BU CTSI’s history of actively engaging in continuous and vigorous dialogue within its own hub, with other CTSA hubs, and with NCATS to identify opportunities to catalyze clinical and translational research locally and nationally. Our goals are: Goal 1. Discover, demonstrate, deploy and disseminate novel programs to develop our entire translational science workforce. Goal 2. Further enhance our robust translational science environment to encourage all aspects of translational research, from scientific discovery to an efficient clinical research enterprise, exploiting our strengths in basic and clinical science, and in so doing address the health disparities of our at risk diverse patients and make the lessons learned and resources developed from our partners and affiliates available to the CTSA network. Goal 3. Effect meaningful multi-directional relationships among all our community stakeholders (patients, providers, purchasers, payers, public policy makers/advocates, product makers and principal investigators) to strengthen collaborative translational research across the lifespan of our special populations and enable novel approaches to integrating research into health care in our ACO. Goal 4. In collaboration with other CTSA Hubs, discover, develop and disseminate innovative tools, methods and programs to improve research on treatments and diagnostics that address our local and national health problems. Goal 5. Develop and demonstrate novel informatics innovations to Improve local Hub translational research in our unique learning health system and disseminate these innovations to the CTSA Network. The BU CTSI’s vision is to be the strongest possible advocate for, and participant in, translational research that serves the health needs of our diverse at risk URG patient populations by empowering our community and creating unique resources that can be integrated with and distributed to the national CTSA network.