A Technology-Based Novel Functional Skills Assessment and Training Program for Adults with and without Cognitive Impairments. Develop the next generation software solution.

有认知障碍的人，如轻度认知障碍（MCI），经常会经历 难以进行日常活动。此外，与年龄有关的标准变化， 认知往往导致以前学到的技能的缺陷，并阻碍新的学习， 学习新的技术体系。这是一个非常令人关注的问题，鉴于人口老龄化， 越来越多的老年人有认知障碍， 日常生活中的新技术。拟议的SBIR第二阶段研究将完善和进一步 评估一种新的基于计算机的综合功能技能评估和培训（CFSAT） 提供对独立生活至关重要的日常任务培训的计划（例如，金融和 药物管理）。程序任务是日常活动的真实表示 和真实的世界系统。培训通过评估部分针对个人量身定制。 研究的第一阶段将涉及对该方案的进一步改进和可用性测试。二期 将涉及40名非受损老年人（NC）和120名MCI成人的随机试验。 MCI参与者将被随机分配到CFSAT条件下，CFSAT结合 基于计算机的认知训练（CCT）条件或主动CCT对照条件。数控 参与者将被分配到CFSAT条件。研究的重要目的是审查 训练和给药的远近转移。我们的设计是高效的，将使我们能够：收集数据 对于受损和未受损的成年人在转移和给药;进一步检查的好处， 对MCI患者进行与CCT相关的直接功能技能培训;以及 确定CCT是否提供了增强CFSAT计划效益的启动效应， 与MCI。我们的主要结果测量包括功能能力的客观测量， 和生态学的即时评估，从自我和 在培训任务域中的线人报告。次要结果包括自我- 有效性、生活质量以及CFSAT计划的可接受性和可用性。我们还将 收集关于保持训练成果、加强训练的需要以及遵守 在家训练。建议的第II期研究的整体目标是制定一个 基于商业可用技术的综合功能技能评估和培训 可以部署在各种技术平台上并用于各种 设置（例如，临床环境、家庭环境）与不同的成年人群。我们的长期 我们的目标是开发一种商业上成功的产品，可以帮助预防和治疗功能性 降低并维持老年人的认知健康和功能独立性。

People with cognitive impairments such as Mild Cognitive Impairment (MCI), often experience difficulty performing everyday routine activities. Further, normative age-related changes in cognition often lead to deficits on previously learned skills and impede new learning such as learning of new technology systems. This is of great concern, given population aging, the increasing number of older adults with cognitive impairments, and the continual deployment of new technologies in everyday contexts. The proposed SBIR Phase II study will refine and further evaluate a novel integrated computer-based functional skills assessment and training (CFSAT) program that provides training on everyday tasks critical to independent living (e.g., financial and medication management). The program tasks are veridical representations of everyday activities and real world systems. The training is tailored to the individual via the assessment component. Phase I of the study will involve further refinement and usability testing of the program. Phase II will involve a randomized trial with 40 non-impaired older adults (NC) and 120 adults with MCI. MCI participants will be randomly assigned to the CFSAT condition, the CFSAT combined with a computer-based cognitive training (CCT) condition, or an active CCT control condition. The NC participants will be assigned to the CFSAT condition. Important aims of the study are to examine near and far transfer of training and dosing. Our design is efficient and will allow us to: gather data for both impaired and non-impaired adults on transfer and dosing; further examine the benefits of direct functional skill training relative to CCT on functional skills (FS) for those with MCI; and determine if CCT provides a priming effect that enhances the benefits of the CFSAT program for those with MCI. Our primary outcome measures include objective measures of functional abilities, and ecological momentary assessment of real-world performance collected from self and informant reports in the training task domains. Secondary outcomes include measures of self- efficacy, quality of life and the acceptability and usability of the CFSAT program. We will also gather data on maintenance of training gains, the need for booster training, and adherence to home-based training. The overall objective of the proposed Phase II study is to develop an integrated commercially available technology-based functional skills assessment and training program that can be deployed on a variety of technology platforms and used in a variety of settings (e.g., clinical settings, home environments) with diverse adult populations. Our long-term goal is to develop a commercially successful product that can help prevent and treat functional declines and maintain the cognitive health and functional independence of older adults.