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Program 15: Cancer Cell Biology

Program 15: Cancer Cell Biology
项目 15:癌细胞生物学
批准号:
10062936
负责人:
JEFFREY W HARPER
金额:
$7.37万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-03-10 至 2021-11-30
关键词:
AreaAttentionBasic Cancer ResearchBasic ScienceBiochemicalBiologyCRISPR/Cas technologyCancer CenterCancer EtiologyCatchment AreaCellsCellular biologyCessation of lifeChemicalsClinicClinical InvestigatorClinical TrialsClinical effectivenessCollaborationsDependenceDevelopmentDiseaseDrug IndustryDrug TargetingEmerging TechnologiesEnzymatic BiochemistryEpigenetic ProcessFosteringFunctional disorderFundingGenerationsGeneticGenome StabilityGenome engineeringGenomicsGoalsHomeHuman GenomeImageIn VitroInstitutionMalignant NeoplasmsMalignant neoplasm of lungMetabolicMethodsMicrofluidicsMissionMultiple MyelomaMutationNeoplasm Circulating CellsNodalNon-Small-Cell Lung CarcinomaNormal CellPaperPathogenesisPathway interactionsPatientsPeer Review GrantsPharmaceutical ChemistryPharmaceutical PreparationsPharmacologic SubstancePharmacologyProcessProteomicsPublicationsPublishingResearch PersonnelResistanceResolutionRoleScienceScientistSignal PathwaySignal TransductionTechnologyThalidomideTherapeuticTranslatingTumor Cell InvasionTumor-DerivedWorkanalytical methodanticancer researchbasebiomarker identificationcancer biomarkerscancer cachexiacancer cellcancer genomecell behaviorchromothripsisclinical translationcostdesigndrug developmentepigenetic regulationfirst-in-humanfundamental researchgenome sequencinggenome-widehomologous recombinationinhibitor/antagonistinter-institutionallight microscopymeetingsmembermetabolomicsneoplastic cellnew technologynovelnovel anticancer drugpatient screeningpersonalized therapeuticprogramsreconstitutionrecruitresistance mechanismsingle cell analysissmall moleculestructural biologytechnology developmenttooltranslational scientisttreatment response

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中文摘要
翻译
癌症细胞生物学计划
英文摘要
Cancer Cell Biology Program Project Summary / Abstract The mission of the Cancer Cell Biology Program is to facilitate basic cancer research and accelerate the application of basic science discoveries in the clinic. The Program has three Specific Aims: 1) To elucidate the pathophysiology of cancer; 2) To support the development and dissemination of new technologies for cancer research; and 3) To facilitate the clinical translation of basic scientific discoveries. The program has 97 members, representing seven DF/HCC institutions and 17 academic departments. In 2014 peer-reviewed grant funding attributed to the Program was $23.8 million in total costs from the NCI and $31.9 million from other sponsors. During the current funding period, Cancer Cell Biology Program members published 1,769 cancer- relevant papers. Of these 24% were inter-institutional, 9% were intra-programmatic, and 34% were inter- programmatic collaborations between two or more DF/HCC members. Overall, when counted once, 27% of DF/HCC publications were inter-programmatic collaborations.
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