Minority Institutional Research Training Program (T32)

项目摘要/摘要 这是心血管研究培训竞赛续签申请的重新提交 27年前在新墨西哥大学(UNM)建立的CRTP项目。它的作用是 为来自代表性不足背景的博士后和博士后实习生提供机会 心血管生物学方面的研究培训。这笔赠款也促进了一项 新墨西哥大学心血管科学研究和培训综合方案。CRTP已将 基础和临床科学，并促进了新的富有成效的学科之间的合作。这一地区 研究和培训的重点与新墨西哥州特别相关，那里的发病率 与心血管相关的疾病很多，特别是在西班牙裔和美洲原住民群体中。 在基金的任期内，发展了几个新的项目，统一了 新墨西哥大学健康科学中心的心血管科学，包括血管的形成 由医学院和药学院的研究人员组成的生理学小组。此外, 自最初资助该奖项以来，UNM HSC已经确定了标志性的研究项目，其中包括一个 重点关注心血管和代谢疾病(CVMD)。这一领域的研究从 研究办公室支持试点研究，并加强其成员之间的合作项目。全 这项资助的导师中有一位是这项签名计划的成员，T32的一名关键成员担任 CVMD项目的负责人。生物医学的结构也促进了合作研究 科学研究生课程，在UNM HSC内提供统一的培训环境。这位毕业生 该计划是非院系的，并在广泛的生物医学科学基础上提供跨学科培训 第一年，随后在选定的学科中进行深入培训。 当前应用程序的目标是在现有框架的基础上继续改进我们的 在研究培训、职业发展、留住和招聘URM科学家方面取得成功。为了促进这一点 后一目标，我们设计了招聘战略，寻求改善我们的计划与 该地区现有的UNM大学和伙伴机构的少数族裔本科课程。我们还将 促进与临床和转化科学中心(CTSC)的临床科学家合作，以 为翻译研究培训提供新的机会。CTSC的领导是这款T32的导师 并将帮助协调CTSC为博士后和博士后学员提供的研究机会。 25名来自基础科学系和临床系的富有成效和协作性的教员 将担任教员导师。CRTP将继续支持6个博士后和2个博士后职位 每年。计划聘期为博士后2-3年，博士后2年。 受训人员，随后由个人培训奖学金或职业指导奖提供支持。

PROJECT SUMMARY/ABSTRACT This is a resubmission of a competitive renewal application for a Cardiovascular Research Training Program (CRTP) that was established 27 years ago at the University of New Mexico (UNM). It has served to provide opportunities for predoctoral and postdoctoral trainees from underrepresented backgrounds to gain research training in cardiovascular biology. This grant has also been a catalyst for the development of an integrated program of research and training in cardiovascular sciences at UNM. The CRTP has bridged the basic and clinical sciences and has fostered new productive collaborations between disciplines. This area of research and training emphasis has particular relevance to the state of New Mexico where the incidence of cardiovascular-related disease is high, especially in the Hispanic and Native American populations. During the tenure of the grant, several new programs have evolved that unify research in the cardiovascular sciences at the UNM Health Sciences Center (HSC), including the formation of the Vascular Physiology Group with researchers from the School of Medicine and the College of Pharmacy. In addition, since the initial funding of the award, the UNM HSC has identified signature research programs including one focused on Cardiovascular and Metabolic Disease (CVMD). This area of research receives special funds from the Office of Research to support pilot studies and to enhance collaborative projects between its members. All of the mentors on this grant are members of this signature program with a key member of the T32 serving as the leader of the CVMD program. Collaborative research is also facilitated by the structure of the Biomedical Sciences Graduate Program that offers a unified training environment within the UNM HSC. The graduate program is non-departmental and provides interdisciplinary training over a broad base of biomedical science in the first year, followed by in-depth training in the chosen discipline. The goals of the current application are to build upon the existing framework and continue to improve our success in research training, career development, retention, and recruitment of URM scientists. To foster this latter objective, we have designed recruitment strategies that seek to improve integration of our program with existing minority-based undergraduate programs at UNM and partner institutions in the region. We will also promote collaborations with clinician scientists in the Clinical and Translational Sciences Center (CTSC) to provide new opportunities for training in translational research. Leaders of the CTSC are mentors on this T32 and will help to coordinate research opportunities in the CTSC for both pre- and post-doctoral trainees. Twenty-five productive and collaborative faculty members from both basic science and clinical departments will serve as faculty mentors. The CRTP will continue to support six predoctoral and two postdoctoral positions per year. Planned appointment durations are 2-3 years for predoctoral students and 2 years for postdoctoral trainees, with subsequent support provided by individual training fellowships or mentored career awards.