Next-generation smart wound dressings for real-time, non-invasive monitoring of infection and neovascularisation in burns

实时评估烧伤的感染和创面进展对于减少并发症和改善长期康复至关重要。我们提出了一种智能敷料，它可以在不需要移除敷料的情况下评估伤口。它由生物兼容的丝膜组成，富含纳米钻石和对pH敏感的荧光团，用于检测感染，并允许对血管再生进行光学评估。该项目将制作并验证智能穿衣的原型，为人体试验做准备。

Real-time assessment of infection and wound progression in burns is critical to reduce complications and improve long-term recovery. We propose a smart dressing that can assess a wound without needing to remove the dressing. It consists of a biocompatible silk membrane enriched with nanodiamonds and pH-sensitive fluorophores to detect infection, and allow optical assessment of blood vessel regrowth. This project will prototype and validate the smart dressing in preparation for human trials.