Psychological and Socio-Environmental Determinants of Sleep and Neurocognitive Function (PEDS)

心理和环境压力以及睡眠障碍是重要的公共卫生问题和 独立已知会显著影响神经认知功能。睡眠受损是一种 慢性疾病的基本风险因素和标志，这些疾病对城市少数群体和 这进一步加剧了健康差距。在睡眠差距方面存在着显著的差距，潜在的作用 环境在这种差异中起到了作用，以及睡眠和神经认知之间的关系 表现可能会受到心理和社会环境特征的影响。建议的目标是 调查是建立一个心理和社会环境特征导致睡眠的模型 干扰神经认知功能的间断。为了实现这一目标，我们将聘用 多模式方法(例如，临床访谈、活动描记、神经行为测试、问卷调查)。 心理因素将通过临床访谈进行评估，社会环境特征的作用将通过 利用一组调查问卷来评估压力环境因素。到时候我们就会有 参与者完成一周的动作描记，以评估客观的睡眠连续性和习惯性睡眠。 最后，我们将利用一个全面的神经认知电池来检查神经认知表现。 研究结果将确定神经认知的特定心理和环境风险因素 表现与习惯性睡眠有关。此外，这些发现将有助于推动该领域朝着 更有用的环境、临床和神经生物学理解的整合，可能会改善 提高生活质量，减少睡眠不平等带来的社会负担。

Psychological and environmental stress, as well as disturbed sleep are important public health concerns and are independently known to significantly influence neurocognitive function. Compromised sleep is an essential risk factor and marker for chronic conditions that disproportionately affect urban minorities and further contribute to health disparities. There is a significant gap regarding sleep disparities, the potential role that the environment plays in such disparities, and how the relationship between sleep and neurocognitive performance may be moderated by psychological and social-environmental features. The goal of the proposed investigation is to establish a model where psychological and social-environmental features elicit sleep discontinuity that interferes with neurocognitive function. To accomplish this goal, we will employ multimodal approaches (e.g. clinical interviews, actigraphy, neurobehavioral tests, questionnaires). Psychological factors will be assessed by clinical interview and the role of social-environmental features by utilizing a battery of questionnaires to assess for stressful environmental factors. We will then have participants complete one week of actigraphy to assess for objective sleep continuity and habitual sleep. Finally, we will examine neurocognitive performance by utilizing a comprehensive neurocognitive battery. Study findings will identify specific psychological and environmental risk factors of neurocognitive performance related to habitual sleep. Further, these findings will be instrumental in moving the field toward a more useful integration of environmental, clinical, and neurobiological understanding that may improve quality of life and reduce the societal burden of sleep disparities.