Center for Machine Learning in Urology-Admin Core

项目总结管理核心 拟议中的费城儿童医院(CHOP)和宾夕法尼亚大学的核心使命 (宾夕法尼亚大学)泌尿学机器学习中心(CMLU)将应用机器学习来提高理解 良性泌尿系疾病的病理生理学、诊断、风险分层和治疗反应预测 儿童和成人之间的疾病。在格雷戈里·塔西安博士的领导下， 管理核心是指导CMLU确保其有效和高效地完成其使命。 为此，行政核心将管理教育丰富方案，并创建 CHOP/Penn中心内部以及其他中心之间的科学协作和交流的基础设施 探索中心和NIDDK资助的项目。通过教育充实计划， 管理核心将促进Kure接受者、UroEpi计划、P20开发中心和 奥布莱恩中心调查人员的知识和专长，印章和宾夕法尼亚大学的调查人员。总体而言， 行政核心计划将通过以下方式增强良性泌尿外科研究社区的实力 与研究基地的互动论坛产生新的想法，提供机器应用方面的培训 学习，并传播研究成果。行政核心将推进 CMLU通过四个协同的具体目标。 1)加强和扩大更大的良性泌尿外科研究社区。 2)为实施CHOP/Penn中心的战略愿景创建基础设施。 3)指导CHOP/宾夕法尼亚中心教育充实计划。 4)评估CHOP/Penn中心的性能。 行政核心的创新结构旨在通过建立关系来打破孤岛 与CHOP和宾夕法尼亚大学以及更广泛的泌尿学研究社区的调查人员合作，并利用 向所有利益攸关方提供CMLU的资源和调查结果。这些创新活动包括指导诊所， 针对实习生和初级调查人员的机构间交流计划、暑期研究奖学金和 年度研究研讨会。此外，我们将提供强大的网络存在，以促进传播和 建立一个研究社区。Web资源包括面向所有人的教育中心和开放访问存储库 CMLU的工作产品，这两个产品都将帮助CHOP/Penn内外的调查人员申请 机器学习工具，用于生成改善对患有良性泌尿系疾病的儿童和成人的护理的知识 疾病。行政核心提供的基础设施将有助于改善个人的成果 并为更广泛的研究社区创造新的机会，学习如何应用机器 学习良性泌尿系统疾病的研究。

PROJECT SUMMARY ADMINISTRATIVE CORE The central mission of the proposed Children’s Hospital of Philadelphia (CHOP) and University of Pennsylvania (Penn) Center for Machine Learning in Urology (CMLU) is to apply machine learning to improve understanding of the pathophysiology, diagnosis, risk stratification, and prediction of treatment responses of benign urological disease among children and adults. Under the leadership of Dr. Gregory Tasian, the purpose of the Administrative Core is to direct the CMLU to ensure that it effectively and efficiently accomplishes its mission. To this end, the Administrative Core will administer the Educational Enrichment Program and create the infrastructure for scientific collaboration and communication within the CHOP/Penn Center and between other Exploratory Centers and NIDDK-funded programs. Through the Educational Enrichment Program, the Administrative Core will facilitate access of KURe recipients, UroEpi programs, P20 Developmental Center and O’Brien Center Investigators to the knowledge and expertise of CHOP and Penn investigators. Collectively, the Administrative Core programs will increase the strength of the benign urologic research community through interactive forums with the research base that generate new ideas, provide training in the application of machine learning, and disseminate research findings. The Administrative Core will advance the central mission of the CMLU through four synergistic Specific Aims. 1) To enhance and expand the larger benign urologic research community. 2) To create the infrastructure for implementing the strategic vision of the CHOP/Penn Center. 3) To direct the CHOP/Penn Center Educational Enrichment Program. 4) To evaluate the performance of the CHOP/Penn Center. The innovative structure of the Administrative Core is designed to break down silos by establishing relationships with investigators within CHOP and Penn and with the broader urologic research community, and availing the resources and findings of the CMLU to all stakeholders. These innovative activities include coaching clinics, interinstitutional exchange programs for trainees and junior investigators, a summer research fellowship, and an annual research symposium. In addition, we will provide a robust web presence to facilitate dissemination and building a research community. Web resources include an educational hub and open-access repository for all work products of the CMLU, both of which will help investigators within and outside of CHOP/Penn to apply machine learning tools to generate knowledge that improves the care for children and adults with benign urologic disease. The infrastructure provided by the Administrative Core will help to improve outcomes for individuals across the lifespan and create new opportunities for the wider research community to learn how to apply machine learning to the study of benign urologic disease.