Pediatric Biopsychology Core

项目总结/摘要 COBRE旨在建立一个项目，支持睡眠研究的卓越和创新， 昼夜节律（CR）和心理健康。连接睡眠、CR科学和儿科心理健康的资源 卫生研究有限，这些领域的研究培训机会缺乏协调的系统， 把这些重要的、相互关联的结构联系起来。儿科生物心理学的总体目标 核心（PBC）是通过将有前途的研究人员与经验丰富的导师联系起来， 加强研究的支持性基础设施，包括对心理健康的循证评估， 睡眠和生物标本的收集为了支持这一总体目标，建设和平委员会的目标是：1）制定一个 通过协调循证评估措施的管理，培养卓越文化， 实践; 2）为数据收集、管理和分析以及技术的使用提供资源- 在睡眠和昼夜节律的背景下研究生物心理学因素的基础资源;以及3） 为生物标本的采集、储存和处理提供资源。PBC将为项目负责人提供 儿科生物心理学评估的个体化指导。核心还将加强多样性， 通过提供对文化敏感的措施和资源来促进包容性。建设和平委员会还将 支持项目负责人按照当前最佳的数据管理程序使用严格的数据管理程序 实践和开放科学指南。核心还将维护一个安全的、符合HIPAA的数据库， 存储多模式和密集型数据流，包括共享评估组，作为 当前和未来的研究。核心的长期目标是：1）开发可持续的资源， 儿科心理评估和生物标本，以加强和促进高质量的研究， 布拉德利医院; 2）为这些数据的管理和分析提供资源;以及3）与 NIH的优先事项，开发一个合并的，集中的数据库，着眼于数据协调。 这些目标的实现将通过提供一种衡量标准， 资源，可以帮助研究人员整合临床护理的需求与共同领域 NIMH研究领域标准（RDoC）框架。拥有一个专注于 将极大地促进COBRE-affiliated项目的研究，以及跨学科的研究。 医院和其他罗得岛设施，帮助协调评估的共同领域， 临床护理和研究项目。这个COBRE将确保布拉德利医院继续成为全州范围内的 在儿童和青少年睡眠和心理健康的研究和护理方面， 性问题

Project Summary/Abstract This COBRE aims to build a program for supporting excellence and innovation in research addressing sleep, circadian rhythms (CR), and mental health. Resources that bridge sleep and CR science and pediatric mental health research are limited, and opportunities for research training in these areas lack a coordinated system to link these important and interconnected constructs. The overall objective of the Pediatric Biopsychological Core (PBC) is to address this gap by connecting promising researchers to experienced mentors and creating a supportive infrastructure for enhancing research that includes evidence-based assessment of mental health, sleep, and the collection of biospecimens. To support this overarching goal, the PBC aims to 1) develop a culture of excellence by coordinating the administration of evidence-based assessment measures and practices; 2) provide resources for data collection, management, and analysis and the use of technology- based resources in the study of biopsychological factors in the context of sleep and circadian rhythms; and 3) provide resources for collection, storage, and processing of biospecimens. The PBC will offer Project Leaders individualized guidance for assessments of pediatric biopsychological. The Core will also enhance diversity in research by offering culturally sensitive measures and resources to promote inclusion. The PBC will also support Project Leaders in using rigorous data management procedures in accordance with current best practice and open science guidelines. The Core will also maintain a secure, HIPAA-compliant database to store multimodal and intensive data streams that will include shared assessment batteries as a resource for current and future research. The long-term goals of the Core are to 1) develop a sustainable resource for pediatric psychological assessment and biospecimens to enhance and promote high-quality research at Bradley Hospital; 2) provide resources for the management and analysis of these data; and 3) consistent with NIH priorities, develop a combined, centralized database with an eye towards data harmonization. Achievement of these aims will result in enhanced research infrastructure by providing a measurement resource that can help researchers integrate the demands of clinical care with the common domains articulated in the NIMH Research Domain Criteria (RDoC) framework. Having a center of excellence focused on measurement will greatly facilitate the research of COBRE-affiliated projects as well as research across the hospital and other Rhode Island facilities by helping to harmonize the assessment of common domains across clinical care and research projects. This COBRE will ensure that Bradley Hospital continues to be a state-wide and national leader in both research and care of children and adolescents with sleep and mental health concerns.