Network Lead Academic Participating Site: Memorial Sloan Kettering Cancer Center

项目总结/摘要 此申请是纪念斯隆凯特琳癌症中心（MSK）的建议，以更新补助金U10 CA 180791 为了保持其作为NCI国家临床研究网络领先学术参与中心的地位， 审判网络（NCTN）。该项目的长期目标和具体目标是让MSK继续 在NCTN试验的发展以及NCTN和NCI的活动中提供科学领导 科学指导委员会，促进NCTN试验的患者招募，并为以下人员提供指导： 临床试验研究的初级研究员。 MSK拥有经过验证的资源，可以为网络带来强大的科学驱动研究， 参与其他网络参与者提出的研究。MSK拥有多学科团队， 研究人员致力于转化研究，大量患者人群适合参与临床研究， 试验和一流的基础设施，以继续成功地支持这种试验。MSK是一个主要成员 肿瘤学和NRG肿瘤学临床试验联盟，以及ECOG的科学主要成员- ACRIN。该网络领先学术研究中心UG 1的多位主要研究者都是经验丰富的领导者 在网络组中，具有满足这些科学，收益和指导目标的跟踪记录。 此外，作为一个专注于癌症的大型中心，MSK拥有特殊的专业知识和承诺， 评估罕见肿瘤的NCTN使命。 !

Project Summary/Abstract This application is Memorial Sloan Kettering Cancer Center's (MSK's) proposal to renew grant U10CA180791 in order to maintain its status as a Network Lead Academic Participating Site for the NCI National Clinical Trials Network (NCTN). The long-term objectives and specific aims of this project are for MSK to continue to provide scientific leadership in the development of NCTN trials and the activities of the NCTN and NCI Scientific Steering Committees, to contribute to patient accrual on NCTN trials, and to provide mentorship to junior investigators in clinical trial research. MSK has the proven resources to both bring strong scientifically driven studies to the network and to participate in studies brought forth by other network participants. MSK has a multidisciplinary team of investigators committed to translational research, a large patient population amenable to participation in clinical trials, and superb infrastructure to continue to successfully support such trials. MSK is a Main Member of Alliance for Clinical Trials in Oncology and NRG Oncology, as well as a Scientific Main Member of ECOG- ACRIN. The multiple Principal Investigators of this Network Lead Academic Site UG1 are experienced leaders in the network groups, with a track record of meeting these scientific, accrual, and mentoring aims. Furthermore, as a large center focused solely on cancer, MSK has a particular expertise and commitment to the NCTN mission of evaluating rare tumors. !