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Assessing the feasibility and acceptability of a Time Restricted Feeding intervention among older adults with Mild Cognitive Impairment

Assessing the feasibility and acceptability of a Time Restricted Feeding intervention among older adults with Mild Cognitive Impairment
评估对患有轻度认知障碍的老年人进行限制时间喂养干预的可行性和可接受性
批准号:
10583672
负责人:
Patrick Josey Smith
金额:
$52.8万
依托单位国家:
美国
项目类别:
财政年份:
2023
资助国家:
美国
项目状态:
未结题
起止时间:
2023-02-01 至 2025-01-31

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中文摘要
翻译
肥胖和相关的代谢合并症与患糖尿病的风险增加了4倍以上。 突发认知障碍,包括阿尔茨海默病和相关痴呆(ADRD)。功能失调 代谢灵活性日益被认为是将代谢风险因素与高血压风险联系起来的关键机制。 认知障碍,尽管很少有研究可移植的行为策略来增强 面临ADRD风险的个人。本研究将审查12周时间的可行性和可接受性 对轻度认知障碍(MCI)患者进行限制性喂养干预。认知和认知能力的变化 新陈代谢功能也将被检查。
英文摘要
Obesity and related metabolic comorbidities have been associated with more than a 4-fold increased risk of incident cognitive impairment, including Alzheimer’s disease and related dementias (ADRD). Dysfunctional metabolic flexibility is increasingly recognized as a critical mechanism linking metabolic risk factors to risk of cognitive impairment, although few studies portable behavioral strategies to enhance metabolic function among individuals at risk for ADRD. The present study will examine the feasibility and acceptability of a 12-week time restricted feeding intervention among individuals with mild cognitive impairment (MCI). Changes in cognitive and metabolic function will also be examined.
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会议论文
Neurocognition, Lifestyle Modification, and Treatment Resistant Hypertension
  • 批准号:
    9197690
  • 项目类别:
  • 资助金额:
    $19.88万
  • 财政年份:
    2016
  • 负责人:
    Patrick Josey Smith
  • 依托单位:
Neurocognition, Lifestyle Modification, and Treatment Resistant Hypertension
  • 批准号:
    9007501
  • 项目类别:
  • 资助金额:
    $21.9万
  • 财政年份:
    2016
  • 负责人:
    Patrick Josey Smith
  • 依托单位:
海外基金