Amplifying Our Voice: Understanding HIV PrEP Promotional Messaging to CreateAuthentic PrEP Content by Men Who Have Sex with Men in the Deep South

1个项目摘要/摘要： 这项K23奖项将允许医学博士罗尼·M·格拉维特在多学科、专家指导下接受培训，成为 3以患者为中心的独立结果研究人员致力于改善影响性行为的艾滋病毒结果 4南方腹地的少数民族。艾滋病病毒对男男性行为者(MSM)的影响不成比例 5深南，美国艾滋病毒新诊断负担最高的地区。预曝光 6预防(PrEP)有效地预防了MSM中艾滋病毒的感染，但PrEP的吸收存在明显的滞后 7与美国其他地区相比，美国南部腹地的坚持性。障碍，如系统性种族主义， 8耻辱和同负性阻碍了MSM充分接触和使用这一有效的策略。高潮 9艾滋病毒负担和PrEP摄入量不足是NIH需要解决的优先事项，例如 10增强能力和有效的PrEP促进战略，以增加PrEP的摄入量。然而，在以下方面存在着严重的差距 11了解艾滋病毒预防信息，这是由交叉身份的更大背景和 12南方腹地男男性接触PrEP的已知障碍。为了解决这一差距，本项目将审查 13用于PrEP宣传消息的首选项，以创建真实且信息丰富的PrEP消息 14通过众包，一种创新的战略，一个团队解决一个共同的问题，解决方案是 15个还给了这个团体。安徒生医疗卫生利用行为模型的整合构建 16社区参与以人为本的设计模式将作为该项目的框架。这 17项目将通过以下具体目标解决这一差距：1)探索PrEP消息传递的首选项 18通过定性访谈在南方腹地的男男性接触者中提供内容，2)使用离散选择实验 19(DCE)，定义PrEP消息传递内容的首选属性，以告知众包格式 20开放呼叫，以及3)将MSM对众包服务的偏好与标准服务进行比较，以告知数字 21旨在增加南方腹地男男性接触者吸食PrEP的干预措施。创建众包内容 22此项目期间将与卫生当局的内容进行比较，以表明社区派生的内容是 23被男男性接触者优先选择。培训计划将结合正式课程、密集研讨会和专家指导。 24集中讨论了以下主题：1)定量、定性和混合方法；2)设计和实施 25个离散的选择实验，以及3)众包以创建真实的PrEP宣传消息。这个K23 26奖项将支持制定肯定的、有效的内容，以改进艾滋病毒预防战略 27 MSM同时还提供来自知名内容和方法专家的指导，结构化， 28协作环境中的多学科培训，以及Gravett博士发展成为 29名独立医生调查员和在深渊的性少数群体中预防艾滋病毒的主要专家 30号公路南段。

1 PROJECT SUMMARY/ABSTRACT: 2 This K23 award will allow Ronnie M. Gravett, MD, to train under multidisciplinary, expert mentorship to become 3 an independent patient-oriented outcomes researcher dedicated to improving the HIV outcomes affecting sexual 4 minority persons in the Deep South. HIV disproportionately affects men who have sex with men (MSM) in the 5 Deep South, a region in the United States with the highest burden of new HIV diagnoses. Pre-exposure 6 prophylaxis (PrEP) effectively prevents HIV acquisition among MSM, but there is a significant lag in PrEP uptake 7 and persistence in the Deep South when compared to other regions of the US. Barriers, such as systemic racism, 8 stigma, and homonegativity, prevent MSM from adequately accessing and using this effective strategy. The high 9 burden of HIV and inadequate PrEP uptake are NIH priorities that need novel strategies to address, such as 10 empowering and effective PrEP promotional strategies to increase PrEP uptake. Yet, there is a critical gap in 11 understanding HIV prevention messaging that is informed by the greater context of the intersecting identities and 12 known barriers to PrEP uptake among MSM in the Deep South. To address this gap, this project will examine 13 preferences for PrEP promotional messaging in order to create authentic and informative PrEP messages 14 through crowdsourcing, an innovative strategy wherein a group solves a common problem and the solution is 15 given back to the group. Integrating constructs of Andersen’s Behavioral Model of healthcare utilization and 16 community engagement into a human-centered design model will serve as the framework for this project. This 17 project will address the gap through the following specific aims: 1) explore preferences for PrEP messaging 18 content among MSM in the Deep South through qualitative interviews, 2) using a discrete choice experiment 19 (DCE), define the preferred attributes for PrEP messaging content to inform the format for the crowdsourcing 20 open call, and 3) compare MSM preferences for crowdsourced services to standard services to inform a digital 21 intervention designed to increase PrEP uptake among MSM in the Deep South. Crowdsourced content created 22 during this project will be compared to health authority content to show that community-derived content is 23 preferred by MSM. The training plan will combine formal coursework, intensive seminars, and expert mentorship 24 focused on the following topics: 1) quantitative, qualitative, and mixed methodologies, 2) design and conduct of 25 discrete choice experiments, and 3) crowdsourcing to create authentic PrEP promotional messaging. This K23 26 award will support the development of affirming, effective content to improve HIV prevention strategies among 27 MSM while also providing mentorship from renowned content and methodological experts, structured, 28 multidisciplinary training in a collaborative environment, and the avenue for Dr. Gravett to develop into an 29 independent physician investigator and leading expert in HIV prevention among sexual minorities in the Deep 30 South.