EPR Spectroscopic Studies of Membrane Proteins-Diversity Supplement

NIGMS（5R35GM126935）的补充--膜的EPR谱研究 蛋白 PA-18 - 906，促进健康相关领域多样性的研究补充 研究 项目总结/摘要 女士Yazmyne Richardson的职业目标是成为一所国立大学的教授。她 喜欢教学和研究，并希望与本科和 研究生。她非常热衷于培养下一代科学家。的 研究培训和职业发展计划在此补充申请是量身定制的， 帮助她实现这个目标。她的研究是目前资助的MIRA项目的关键部分 通过NIGMS。她将有一个积极的支持网络的教师和工作人员，以帮助她导航 实现职业目标的途径。教授。加里洛里根将是主要的导师和教授卡罗尔 Dabney-Smith和Andrea Kravats教授将担任共同导师。以下人员在 迈阿密大学还将为她提供有价值的研究和职业发展培训。 罗伯·麦卡里克，安妮·卡罗尔医生，雅斯敏·伊沙，和安德鲁·莫里斯医生。应用程序已 研究和职业发展计划 研究培训计划：Yazmyne Richardson女士的研究培训计划将与 和米拉·奈姆斯的资助完美结合她博士学位的重点。论文工作将是发展 使用多种方法改进膜蛋白结构研究的新方法 生物物理技术她正在开发新的生物物理方法与聚合物， 纳米盘，以更好地研究膜蛋白的结构和动态特性， 各种结构和生物物理技术。yazmyne会接受大量的生物物理学训练 仪器（EPR和NMR光谱）和标准分子生物学/生物化学 帮助她在实验室制备膜蛋白样品的方法。她已经学会了 表达和纯化KCNE1蛋白并将其掺入脂质体中。 职业发展计划：PI（加里洛里根）和化学系在迈阿密 大学将能够帮助Yazmyne Richardson通过提供 众多的专业发展机会。她将学习生物物理学课程， 提高教学技能的方法。她将学习如何进行科学研究的课程 向公众介绍。Lorigan博士将给她的反馈和建设性的批评， 她的科学成果和她的演讲能力。Yazmyne将参加几个会议， 她的研究生培训，并给出海报和口头报告。她将有机会 少数民族学生生物医学研究年会（ABRCMS）她 我将参加几个专业发展会议，讨论研究的发展 提案、安全、科学报告、科学伦理、职业。她将参加格兰特 写作研讨会，以帮助她发展技能，成为一个独立的PI。她会得到 由两位成功女性（Carole Dabney-Smith教授和Andrea Kravats教授）共同指导。 最后，理查森女士还将作为一个榜样和导师，本科生在 刘易斯斯托克斯少数民族参与联盟（LSAMP）联盟计划。richardson女士 每年都会和她的论文委员会开会讨论她的研究进展。 Lorigan教授她的论文导师每周都会和她见面讨论她的研究 和教学进步，以帮助她实现她的职业目标。 1

A Supplement to: NIGMS (5R35GM126935)--EPR Spectroscopic Studies of Membrane Proteins In Response to: PA-18-906, Research Supplement to Promote Diversity in Health-Related Research Project Summary/Abstract Ms. Yazmyne Richardson career goal is to become a professor at a national University. She enjoys teaching and research and wants to work with a combination of undergraduate and graduate students. She is very passionate about training the next generation of scientists. The research training and career development plan in this supplement application is tailor-made to help her achieve this goal. Her research is a critical part of the MIRA project currently funded by NIGMS. She will have an active support network of faculty and staff to help her navigate a path to achieve her career goals. Prof. Gary Lorigan will be the main mentor and Prof. Carole Dabney-Smith and Prof. Andrea Kravats will serve as co-mentors. The following individuals at Miami University will also provide valuable research and career development training for her: Dr. Rob McCarrick, Dr. Anne Carroll, Yasmin Jessa, and Dr. Andrew Morris. The application has a research and career development plan Research Training Plan: The research training plan for Ms. Yazmyne Richardson will match perfectly with the MIRA NIGMS grant. The focus of her Ph.D. dissertation work will be to develop new methods to improve structural studies of integral membrane proteins using a variety of biophysical techniques. She is developing new biophysical methods with polymers to serve as nanodiscs to better study the structural and dynamic properties of membrane proteins using a variety of structural and biophysical techniques. Yazmyne will get lots of training in biophysical instrumentation (EPR and NMR spectroscopy) and standard molecular biology/biochemistry methods to help her prepare the membrane protein samples in the lab. She has already learned to express and purify the KCNE1 protein and incorporate it into liposomes. Career Development Plan: The PI (Gary Lorigan) and the Department of Chemistry at Miami University will be able to help Yazmyne Richardson obtain her career goals by providing numerous professional development opportunities. She will take courses in biophysics and methods to improve her teaching skills. She will take courses on how to give scientific presentations for the public. Dr. Lorigan will give her feedback and constructive criticism on both her scientific results and her speaking ability. Yazmyne will attend several conferences as part of her graduate training and give posters and oral presentations. She will have the opportunity to attend the Annual Biomedical Research Conference for Minority Students (ABRCMS). She will attend several professional development sessions that discuss the development of research proposals, safety, scientific presentations, ethics in science, careers. She will attend grant writing workshops to help her develop the skill set to become an independent PI. She will get co-mentored by 2 successful women (Prof. Carole Dabney-Smith and Prof. Andrea Kravats). Finally, Ms. Richardson will also serve as a role model and mentor to undergraduate students in the Lewis Stokes Alliance for Minority Participation (LSAMP) Alliance program. Ms. Richardson will meet up every year with her dissertation committee to discuss her research progress. Professor Lorigan her dissertation advisor will meet up with her weekly to discuss her research and teaching progress to help her achieve her career goals. 1