Suubi+Adherence-R2: Examining the longitudinal HIV treatment adherence among youth living with HIV (YLHIV) transitioning into young adulthood

项目摘要/摘要 Suubi+Advisence-R2行政补充项目的目的是增强 通过招募乌干达艾滋病毒携带者(RYLHIV)难民青年将目标人口纳入其中。 虽然父母补助金侧重于感染艾滋病毒的青年，但不包括难民青年。 人口。然而，难民青年是非常脆弱的人群，感染艾滋病毒的风险增加。 由于剥削，因为他们中的许多人可能没有父母或监护人和许多人陪伴 曾遭受基于性别的暴力，包括在#年被用作战争武器的强奸 他们正在逃离的冲突。此外，这些难民中的许多人现在定居在一些地区 是乌干达艾滋病毒感染率最高的国家之一。这增加了人们感染艾滋病毒的风险 难民人口的情况更加复杂，因为这些难民青年中的许多人 一般的性健康和生殖健康知识。此外，艾滋病毒检测率为 由于缺乏隐私等障碍，这些难民社区的人口比例较低 难民营、交通困难、识字和语言困难、耻辱和艾滋病毒检测是 难民往往不是最优先事项，因为他们全神贯注于基本生存所必需的活动。 此外，鉴于创伤相关精神障碍的高流行率，由于其 暴露在创伤中，再加上他们陷入的赤贫 流离失所，这已被证明增加了危险性行为的参与率 和药物使用，这些青少年难民感染或感染 传播艾滋病毒和其他性传播疾病。与父母赠款的目标一致，行政管理 补充将使我们能够：检查艾滋病毒病毒抑制(主要结果)并探索 参与者获取和补充处方药物的能力，坚持每日处方 常规用药，并从事艾滋病毒护理；以及(2)评估a)经济稳定性、性风险- 采取行为，坚持自我效能感；b)认知功能；c)心理健康功能； 以及d)年轻人的过渡和社会支持。这一行政副刊意义重大 因为它有可能促进我们对包括艾滋病毒利用在内的各种因素的理解 治疗和坚持治疗，创伤相关障碍，心理功能， 以及乌干达弱势难民青年人口的性决策。

PROJECT SUMMARY/ABSTRACT The purpose of the Suubi+Adherence-R2 administrative supplemental project is to enhance inclusion of the target population by recruiting refugee youth living with HIV (RYLHIV) in Uganda. While the parent grant focuses on youth living with HIV, it does not include refugee youth population. Yet, refugee youth are a very vulnerable population at increased risk of HIV infection due to exploitation as many of them may be unaccompanied by parents or guardians and many have been exposed to gender-based violence including rape that is used as a weapon of war in the conflicts they are fleeing from. Moreover, many of these refugees are now settled in areas with some of the highest HIV rates in Uganda. This elevated risk of HIV infection among the refugee population is compounded by the fact that many of these refugee youth have very limited knowledge about sexual and reproductive health in general. Additionally, HIV testing rates are low in these refugee communities due to barriers such as lack of privacy from overcrowding in camps, transportation difficulties, literacy and language difficulties, stigma, and HIV testing is often not the top priority as refugees are preoccupied by activities necessary for basic survival. Additionally, given the high prevalence of trauma-associated mental disorders due to their exposure to trauma, compounded by the abject poverty that they have been thrown into by displacement, that have been shown to increase the rates of engagement in risky sexual behavior and substance use, these adolescent refugees are at especially increased risk of acquiring or transmitting HIV and other STIs. Consistent with the aims of the parent grant, the administrative supplement will allow us to: examine the HIV viral suppression (primary outcome) and explore the participants' ability to access and refill prescribed medication, adhere to prescribed daily medication routines, and engage in HIV care; and (2) assess a) economic stability, sexual risk- taking behavior, adherence self-efficacy; b) cognitive functioning; c) mental health functioning; and d) young adult transitions and social support. This administrative supplement is significant because it has the potential to advance our understanding of factors including utilization of HIV treatment and adherence to treatment, trauma-associated disorders, psychological functioning, and sexual decision-making among vulnerable refugee youth population in Uganda.