Bioinformatics Core

生物信息学核心项目总结 缅因州IDEA生物医学研究卓越网络（ME-INBRE）生物信息学核心将支持 通过提供生物信息学方面的基本咨询和培训，开展比较功能基因组学研究。 生物医学研究越来越多地利用高通量技术，核心将提供 管理、分析和解释大型数据集所需的专业知识。专家核心工作人员将 建议和/或与ME-INBRE研究人员合作，在实验中应用最佳实践 基因组数据分析的设计、数据管理和最先进的工作流程，特别关注 严谨性和可重复性。核心人员还将为ME-INBRE项目负责人提供访问和专业知识 在使用适当的网络基础设施跨越本地，区域和云计算资源。的 生物信息学核心将利用东北地区的区域合作和网络基础设施 ME-INBRE与其他四个IDEA州共同创立的网络基础设施联盟（NECC）， 区域网络基础设施，并开展协作性网络研究。通过东北 生物信息学合作（NEBC），核心将与INBRE生物信息学核心工作人员在特拉华州， 新罕布什尔州、罗得岛和佛蒙特州的咨询项目，以支持缅因州的教师和合作 为教师和学生提供生物信息学培训。区域网络基础设施将用于 密集计算和集中数据存储、共享和备份。核心将维持并建造 生物信息学培训班和讲习班， 本科水平的教师调查，并将继续支持缅因州的专业大学 硕士在生物信息学计划和生物信息学学者计划，这提供了宝贵的 为ME-INBRE伙伴机构的学生提供生物信息学研究培训。总之，核心将 提供ME-INBRE科学家所需的生物信息学知识和技术专长以及培训， 实现他们的研究目标。

BIOINFORMATICS CORE PROJECT SUMMARY The Maine IDeA Network for Biomedical Research Excellence (ME-INBRE) Bioinformatics Core will support research in comparative functional genomics by providing essential consulting and training in bioinformatics. Biomedical research increasingly utilizes high throughput technologies, and the Core will provide the specialized expertise needed for managing, analyzing and interpreting large data sets. Expert Core staff will advise and/or collaborate with ME-INBRE researchers in the application of best practices in experimental design, data management, and state-of-the-art workflows for genomic data analysis, with a particular focus on rigor and reproducibility. Core personnel will also provide ME-INBRE Project Leaders access to and expertise in the use of appropriate cyberinfrastructure spanning local, regional, and Cloud computing resources. The Bioinformatics Core will leverage regional collaborations and cyberinfrastructure through the Northeast Cyberinfrastructure Consortium (NECC) that ME-INBRE cofounded with four other IDeA states to expand regional cyberinfrastructure and conduct collaborative cyber enabled research. Through the Northeast Bioinformatics Collaborative (NEBC), the Core will work with INBRE Bioinformatics Core staff in Delaware, New Hampshire, Rhode Island, and Vermont on consulting projects to support Maine faculty and collaborate on delivering bioinformatics training to faculty and students. Regional cyberinfrastructure will be used for intensive computation and centralized data storage, sharing and backup. The Core will maintain and build upon its established bioinformatics training courses and workshops, which address audiences ranging from the undergraduate level to faculty investigators, and will continue to support the University of Maine’s Professional Master’s in Bioinformatics program and Bioinformatics Scholars Program, which provide valuable bioinformatics research training for students at ME-INBRE partner institutions. In summary, the Core will provide the intellectual and technical expertise and training in bioinformatics that ME-INBRE scientists need to accomplish their research goals.