Novel nanotechnology strategies for drug co-delivery and combined therapies in the brain

治疗脑部疾病的主要挑战包括将药物有效地输送到大脑和有针对性地输送到致病区域。我开发了两种世界首创的药物输送系统来应对这些挑战。该项目将扩大它们的负载和大脑传递能力，为大脑中的目标部位提供广泛的新型多种治疗方法。人类大脑疾病模型将用于系统的临床前评估新的输送系统和治疗方法。

Key challenges for treating brain diseases include effective delivery of drugs into the brain and targeted delivery to pathogenic areas. I have developed two world-first drug delivery systems that address these challenges. This project will expand their loading and brain delivery capability to deliver a broad range of novel multiple therapeutics to target sites in the brain. Human brain disease models will be used for systematic preclinical evaluation of novel delivery systems and therapeutics.