Minority Institutional Research Training Program (T32)
Minority Institutional Research Training Program (T32)
批准号:
10625296
负责人:
THOMAS C RESTA
金额:
$47.18万
依托单位国家:
美国
项目类别:
财政年份:
1993
资助国家:
美国
项目状态:
未结题
起止时间:
1993-07-01 至 2026-04-30
中文摘要
项目总结/摘要
这是心血管研究培训的竞争性更新申请的重新提交
该计划(CRTP),成立于27年前在新墨西哥州(UNM)的大学。它已经服务于
为来自代表性不足背景的博士前和博士后学员提供机会,
心血管生物学的研究培训。这笔赠款也促进了
在UNM心血管科学的研究和培训的综合计划。CRTP已将
基础和临床科学,并促进了学科之间新的富有成效的合作。的这个区域
研究和培训重点与新墨西哥州特别相关,
心血管相关疾病的发病率很高,尤其是在西班牙裔和美洲土著人群中。
在赠款的任期内,几个新的计划已经发展,统一研究,
在UNM健康科学中心(HSC)的心血管科学,包括形成血管
生理学小组由医学院和药学院的研究人员组成。此外,本发明还提供了一种方法,
自从该奖项获得最初的资助以来,北卡罗来纳大学HSC已经确定了一些标志性的研究项目,其中包括一个
心血管和代谢疾病(CVMD)。该研究领域获得了以下机构的专项资金
研究办公室,以支持试点研究,并加强其成员之间的合作项目。所有
在这个补助金的导师是这个签名计划的成员与T32的关键成员担任
CVMD项目的负责人合作研究也促进了生物医学的结构,
科学研究生课程,提供了一个统一的培训环境内UNM HSC。研究生
计划是非部门,并提供跨学科的培训,在生物医学科学的广泛基础,
第一年,然后是所选学科的深入培训。
当前应用程序的目标是在现有框架的基础上继续改进我们的
在研究培训,职业发展,保留和招聘URM科学家的成功。为了培养这种
后一个目标,我们设计了招聘策略,寻求改善我们的计划与
UNM和该地区合作机构现有的少数民族本科课程。我们还将
促进与临床和转化科学中心(CTSC)的临床科学家的合作,
为转化研究提供新的培训机会。CTSC的领导是T32的导师
并将帮助协调CTSC的研究机会,为博士前和博士后学员。
来自基础科学和临床部门的25名富有成效和协作的教师
将担任教师导师。CRTP将继续支持六个博士前和两个博士后职位
每一年。博士生计划聘期为2-3年,博士后为2年
学员,随后由个人培训研究金或辅导职业奖提供支助。
英文摘要
PROJECT SUMMARY/ABSTRACT
This is a resubmission of a competitive renewal application for a Cardiovascular Research Training
Program (CRTP) that was established 27 years ago at the University of New Mexico (UNM). It has served to
provide opportunities for predoctoral and postdoctoral trainees from underrepresented backgrounds to gain
research training in cardiovascular biology. This grant has also been a catalyst for the development of an
integrated program of research and training in cardiovascular sciences at UNM. The CRTP has bridged the
basic and clinical sciences and has fostered new productive collaborations between disciplines. This area of
research and training emphasis has particular relevance to the state of New Mexico where the incidence of
cardiovascular-related disease is high, especially in the Hispanic and Native American populations.
During the tenure of the grant, several new programs have evolved that unify research in the
cardiovascular sciences at the UNM Health Sciences Center (HSC), including the formation of the Vascular
Physiology Group with researchers from the School of Medicine and the College of Pharmacy. In addition,
since the initial funding of the award, the UNM HSC has identified signature research programs including one
focused on Cardiovascular and Metabolic Disease (CVMD). This area of research receives special funds from
the Office of Research to support pilot studies and to enhance collaborative projects between its members. All
of the mentors on this grant are members of this signature program with a key member of the T32 serving as
the leader of the CVMD program. Collaborative research is also facilitated by the structure of the Biomedical
Sciences Graduate Program that offers a unified training environment within the UNM HSC. The graduate
program is non-departmental and provides interdisciplinary training over a broad base of biomedical science in
the first year, followed by in-depth training in the chosen discipline.
The goals of the current application are to build upon the existing framework and continue to improve our
success in research training, career development, retention, and recruitment of URM scientists. To foster this
latter objective, we have designed recruitment strategies that seek to improve integration of our program with
existing minority-based undergraduate programs at UNM and partner institutions in the region. We will also
promote collaborations with clinician scientists in the Clinical and Translational Sciences Center (CTSC) to
provide new opportunities for training in translational research. Leaders of the CTSC are mentors on this T32
and will help to coordinate research opportunities in the CTSC for both pre- and post-doctoral trainees.
Twenty-five productive and collaborative faculty members from both basic science and clinical departments
will serve as faculty mentors. The CRTP will continue to support six predoctoral and two postdoctoral positions
per year. Planned appointment durations are 2-3 years for predoctoral students and 2 years for postdoctoral
trainees, with subsequent support provided by individual training fellowships or mentored career awards.
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Antioxidant and vasodilatory effects of heme oxygenase on mesenteric vasoreactivity following chronic hypoxia.
血红素加氧酶对慢性缺氧后肠系膜血管反应性的抗氧化和血管舒张作用。
DOI:
10.1080/10739680802342077
发表时间:
2009
期刊:
Microcirculation (New York, N.Y. : 1994)
影响因子:
--
作者:
[Sweazea,Karen, Walker,BenjimenR]
通讯作者:
Walker,BenjimenR
DOI:
10.1371/journal.pone.0079245
发表时间:
2013
期刊:
PloS one
影响因子:
3.7
作者:
[Meyer MR, Fredette NC, Barton M, Prossnitz ER]
通讯作者:
Prossnitz ER
DOI:
10.1371/journal.pone.0180455
发表时间:
2017
期刊:
PloS one
影响因子:
3.7
作者:
[Jernigan NL, Naik JS, Weise-Cross L, Detweiler ND, Herbert LM, Yellowhair TR, Resta TC]
通讯作者:
Resta TC
DOI:
10.1038/onc.2015.449
发表时间:
2016-08-04
期刊:
Oncogene
影响因子:
8
作者:
[Marjon KD, Termini CM, Karlen KL, Saito-Reis C, Soria CE, Lidke KA, Gillette JM]
通讯作者:
Gillette JM
DOI:
10.1161/circresaha.110.228999
发表时间:
2011-06-10
期刊:
Circulation research
影响因子:
20.1
作者:
[Jackson-Weaver O, Paredes DA, Gonzalez Bosc LV, Walker BR, Kanagy NL]
通讯作者:
Kanagy NL
共 44 条
Oxidant Signaling in Pulmonary Hypertension
-
批准号:10720584
-
项目类别:
-
资助金额:$58.62万
-
财政年份:2023
-
负责人:THOMAS C RESTA
-
依托单位:
Vascular Smooth Muscle Signaling in Intermittent Hypoxia-Induced Pulmonary Hypertension
-
批准号:9330238
-
项目类别:
-
资助金额:$37.88万
-
财政年份:2016
-
负责人:THOMAS C RESTA
-
依托单位:
Pulmonary Vasoreactivity Following Chronic Hypoxia
-
批准号:7843686
-
项目类别:
-
资助金额:$37.5万
-
财政年份:2008
-
负责人:THOMAS C RESTA
-
依托单位:
Pulmonary Vasoreactivity Following Chronic Hypoxia
-
批准号:8269812
-
项目类别:
-
资助金额:$37.13万
-
财政年份:2008
-
负责人:THOMAS C RESTA
-
依托单位:
Pulmonary Vasoreactivity Following Chronic Hypoxia
-
批准号:7522559
-
项目类别:
-
资助金额:$37.5万
-
财政年份:2008
-
负责人:THOMAS C RESTA
-
依托单位:
Pulmonary Vasoreactivity Following Chronic Hypoxia
-
批准号:7651337
-
项目类别:
-
资助金额:$37.5万
-
财政年份:2008
-
负责人:THOMAS C RESTA
-
依托单位:
NO-Mediated Pulmonary Vasodilation After Chronic Hypoxia
-
批准号:7081293
-
项目类别:
-
资助金额:$32.96万
-
财政年份:2004
-
负责人:THOMAS C RESTA
-
依托单位:
NO-Mediated Pulmonary Vasodilation After Chronic Hypoxia
-
批准号:6908966
-
项目类别:
-
资助金额:$33.75万
-
财政年份:2004
-
负责人:THOMAS C RESTA
-
依托单位:
Nitric Oxide-Mediated Pulmonary Vasodilation After Chronic Hypoxia
-
批准号:7236634
-
项目类别:
-
资助金额:$32.0万
-
财政年份:2004
-
负责人:THOMAS C RESTA
-
依托单位:
NO-Mediated Pulmonary Vasodilation After Chronic Hypoxia
-
批准号:6816887
-
项目类别:
-
资助金额:$33.75万
-
财政年份:2004
-
负责人:THOMAS C RESTA
-
依托单位:
CORE--ANALYTICAL EQUIPMENT
-
批准号:6972155
-
项目类别:
-
资助金额:$13.77万
-
财政年份:2004
-
负责人:THOMAS C RESTA
-
依托单位:
ESTRADIOL MEDIATED INHIBITION OF PULMONARY HYPERTENSION
-
批准号:6972146
-
项目类别:
-
资助金额:$13.77万
-
财政年份:2004
-
负责人:THOMAS C RESTA
-
依托单位:
VASODILATORY MECHANISMS DURING PULMONARY HYPERTENSION
-
批准号:6030440
-
项目类别:
-
资助金额:$2.2万
-
财政年份:1999
-
负责人:THOMAS C RESTA
-
依托单位:
VASODILATORY MECHANISMS DURING PULMONARY HYPERTENSION
-
批准号:2735014
-
项目类别:
-
资助金额:$3.15万
-
财政年份:1998
-
负责人:THOMAS C RESTA
-
依托单位:
VASODILATORY MECHANISMS DURING PULMONARY HYPERTENSION
-
批准号:2412986
-
项目类别:
-
资助金额:$2.96万
-
财政年份:1997
-
负责人:THOMAS C RESTA
-
依托单位:
Minority Institutional Research Training Program (T32)
-
批准号:9144898
-
项目类别:
-
资助金额:$35.72万
-
财政年份:1993
-
负责人:THOMAS C RESTA
-
依托单位:
Minority Institutional Research Training Program (T32)
-
批准号:10112639
-
项目类别:
-
资助金额:$43.37万
-
财政年份:1993
-
负责人:THOMAS C RESTA
-
依托单位:
Minority Institutional Research Training Program (T32)
-
批准号:9922330
-
项目类别:
-
资助金额:$20.44万
-
财政年份:1993
-
负责人:THOMAS C RESTA
-
依托单位:
Minority Institutional Research Training Program (T32)
-
批准号:10400006
-
项目类别:
-
资助金额:$37.24万
-
财政年份:1993
-
负责人:THOMAS C RESTA
-
依托单位:
海外基金