Training Program in Reproductive, Perinatal and Pediatric Epidemiology

摘要 从怀孕到成年的过程受到许多因素的影响，包括遗传，社会因素， 营养、感染、炎症和环境。这些因素的影响取决于类型和 相对于脆弱性的关键窗口，暴露的时间。实验科学专注于 了解、测量和干预影响生殖和儿科健康的因素， 由于这些人群天生的脆弱性，这一点尤其具有挑战性。流行病学提供了一个严格的 询问有关生殖、围产期和儿科健康的重要问题的方法框架 和疾病流行病学家接受培训，以估计生殖和儿科疾病的患病率， 一系列暴露和结果之间的因果关系，以及社会决定因素在 造成健康差距。流行病学方法对于评估 采取干预措施，改善生殖和儿科健康成果。严格的方法定制研究设计， 最大限度地提高数据质量，仔细构建分析，以尽量减少偏见，强调解释。我们 生殖，围产期和儿科流行病学博士前培训计划准备下一个 一代流行病学家调查遗传学的真实的世界背景和相互作用的影响， 影响生殖、围产期和儿科健康的物理环境和社会环境。培训 包括教学培训和指导研究，辅以专业发展， 丰富的机会。主要和附属导师有广泛的研究组合和一系列的 专业知识提供。受训者对生殖和儿科的生物学基础表示赞赏 健康他们学会识别长期存在和新出现的问题，并应用严格的研究方法， 复杂的真实世界的环境来研究它们。学员完成我们的计划与复杂的 方法工具箱，将方法与实质性领域知识相结合的经验， 专业技能，从事合作科学，推进该领域和解决重要的研究 影响生殖健康和儿童健康的问题。

ABSTRACT The pathway from conception to adulthood is influenced by many factors including genetics, social factors, nutrition, infection and inflammation and the environment. The impact of these factors depends on the type and timing of exposures, relative to critical windows of vulnerability. Experimental science focused on understanding, measuring, and intervening on factors that influence reproductive and pediatric health is especially challenging due to the innate vulnerability of these populations. Epidemiology provides a rigorous methodological framework to interrogate important questions about reproductive, perinatal, and pediatric health and disease. Epidemiologists are trained to estimate the prevalence of reproductive and pediatric conditions, causal relationships between a range of exposures and outcomes, and the role social determinants play in creating health disparities. Epidemiologic methods are also valuable for evaluating the implementation of interventions to improve reproductive and pediatric health outcomes. Rigorous methods tailor study design to maximize data quality and carefully construct analyses to minimize bias and emphasize interpretation. Our Reproductive, Perinatal, and Pediatric Epidemiology Predoctoral Training Program prepares the next generation of epidemiologists to investigate the real world contextual and interacting influences of genetics, physical environment, and social environment that impact reproductive, perinatal, and pediatric health. Training comprises didactic training and mentored research, complemented with professional development and enrichment opportunities. Primary and Affiliate Preceptors have extensive research portfolios and a range of expertise to offer. Trainees gain appreciation for the biological underpinnings of reproductive and pediatric health. They learn to identify longstanding and emerging problems and apply rigorous research methods in complex, real-world settings to study them. Trainees complete our program with a sophisticated methodological toolbox, experience integrating methods with substantive area knowledge, and requisite professional skills to engage in collaborative science that advances the field and tackles important research questions that impact reproductive and child health.