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中文摘要
翻译
摘要 来自RR&D中心肢体丧失和活动能力(REGISE)的七名调查人员正在申请资金以增强 他们现有的双平面透视系统。该系统将支持正在努力实现的各种项目 该中心的核心使命是改善处于危险中的两名退伍军人的生活质量和功能状况 适用于下肢截肢,以及退伍军人和曾接受过下肢截肢的服役人员 截肢。 攀登的双平面透视实验室(101号楼,GW11室)是一个750平方英尺的空间,其中 双平面透视系统和我们的定制分析软件星座。一对X射线成像系统 当研究对象执行功能性任务时,同时记录脚部的骨骼运动。少校 两个X射线臂的每个部件是:a)X射线管(G-1082型,VAREX成像,盐湖城, UT),B)40厘米X射线图像增强器(TH 9447型,泰利斯电子设备,法国莫伊兰),C)高- 电压X射线发生器(Epsilon,EMD Technologies,魁北克,加拿大),D)可伸缩天花板安装管 起重机(Halo,CORELabs,Englewood,CO),E)X射线光束准直器(R225型,Ralco Medical 组件,El Dorado Hills,CA)和F)高速摄像机(Phantom v641,Vision Research,Wayne, 新泽西州)。自定义计时模块确保这两个系统产生脉冲(高达150帧/秒)或 同步连续进行X光检查。该系统主要由成像系统公司和 SERVICE,INC(俄亥俄州佩恩斯维尔),我们的团队贡献了走道和图像增强器支架的设计。 对于这项SHEEP建议,我们的目标是通过有效地临时取代非法入境者和 带两个数字射线照相(DR)平板的高速摄像机(VAREX XD43X43 R/F),可定制 支撑架、格栅和保护架。灾难恢复面板还需要一些自定义软件 发展。我们将从成像系统公司购买升级后的系统硬件和软件 该公司还提供了现有的双翼飞机系统硬件。DR面板将使您可以轻松 重新配置双平面实验室,以研究经胫骨或经股动脉等病理情况下的双腿 截肢、膝骨性关节炎或股骨远端骨折。 双平面透视系统将支持该中心研究范围内的一些项目, 包括:1)经胫窝配合;2)经股窝配合;3)经股对侧膝关节炎;4)膝关节 背包负重时的力学;5)股骨远端骨折部位的运动。
英文摘要
ABSTRACT Seven Investigators from the RR&D Center for Limb Loss and MoBility (CLiMB) are requesting funds to augment their existing biplane fluoroscopy system. This system will support a variety of projects that are working towards the Center’s core mission of improving the quality of life and functional status of both Veterans who are at risk for lower extremity amputation, and Veterans and service members who have undergone lower extremity amputation. CLiMB’s Biplane Fluoroscopy Laboratory (Bldg. 101, room GW11) is a 750 sq ft space in which resides the Biplane Fluoroscopy System and our custom analysis software, Constellation. A pair of X-ray imaging systems concurrently record bone motion of the foot while a research subject performs functional tasks. The major components of each of the two X-ray arms are: A) an X-ray tube (Model G-1082, Varex Imaging, Salt Lake City, UT), B) a 40 cm X-ray image intensifier (Model TH 9447, Thales Electron Devices, Moirans, France), C) a high- voltage X-ray generator (Epsilon, EMD Technologies, Quebec, Canada), D) a telescoping ceiling-mounted tube crane (HALO, CORElabs, Englewood, CO), E) an X-ray beam collimator (Model R 225, Ralco Medical Components, El Dorado Hills, CA), and F) a high-speed video camera (Phantom v641, Vision Research, Wayne, NJ). A custom timing module ensures that these two systems generate pulsed (up to 150 frames/second) or continuous X-rays synchronously. The system was mostly designed and developed by Imaging Systems and Service, Inc (Painesville, OH), with our group contributing the walkway and image intensifier stand designs. For this ShEEP proposal, we aim to augment the biplane system by effectively temporarily replacing the IIs and high speed video cameras with two digital radiography (DR) flat panels (Varex XRD 43X43 R/F) with custom support stands, grids, and protective holders. The DR panels will also require some custom software development. We will be purchasing the upgraded system hardware and software from Imaging Systems and Service, Inc., who also provided the existing biplane system hardware. The DR panels will allow for the easy reconfiguration of the biplane laboratory to study lower limbs for such pathologies as transtibial or transfemoral amputations, knee osteoarthritis, or distal femur fractures. The biplane fluoroscopy system will support a number of projects that span the Center’s research portfolio, including: 1) trans-tibial socket fit; 2) trans-femoral socket fit; 3) trans-femoral contralateral knee arthritis; 4) knee mechanics during backpack loading; and 5) distal femur fracture site motion.
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会议论文
Characterizing and Restoring Joint Motion in Patients with Hallux Rigidus: Human Subject Testing
  • 批准号:
    10710384
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    2020
  • 负责人:
    William R. Ledoux
  • 依托单位:
Characterizing and Restoring Joint Motion in Patients with Hallux Rigidus: Human Subject Testing
  • 批准号:
    10262929
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    2020
  • 负责人:
    William R. Ledoux
  • 依托单位:
Characterizing and Restoring Joint Motion in Patients with Hallux Rigidus
Characterizing and Restoring Joint Motion in Patients with Hallux Rigidus
国内基金
海外基金
ANKLE2通过调控PINK1减轻脓毒症心肌细胞线粒体钙超载的机制研究
  • 批准号:
    CSTB2023NSCQ-MSX0603
  • 项目类别:
    省市级项目
  • 资助金额:
    10.0万元
  • 批准年份:
    2023
  • 负责人:
    许皓
  • 依托单位:
影响核膜与内质网膜结构的ANKLE2分子在衰老调控中的关键作用
  • 批准号:
    91649107
  • 项目类别:
    重大研究计划
  • 资助金额:
    60.0万元
  • 批准年份:
    2016
  • 负责人:
    朱正茂
  • 依托单位: