SERVICES FOR THE CHARACTERIZATION OF ABSORPTION, DISTRIBUTION, METABOLISM, EXCRETION, AND TOXICITY (ADMET) PROPERTIES OF SMALL-MOLECULE DRUG CANDIDATES USING STANDARDIZED IN VITRO METHODS IN SUPPORT O
SERVICES FOR THE CHARACTERIZATION OF ABSORPTION, DISTRIBUTION, METABOLISM, EXCRETION, AND TOXICITY (ADMET) PROPERTIES OF SMALL-MOLECULE DRUG CANDIDATES USING STANDARDIZED IN VITRO METHODS IN SUPPORT O
使用标准化体外方法表征小分子候选药物的吸收、分布、代谢、排泄和毒性 (ADMET) 特性的服务
批准号：
10936131
负责人：
RALF GEIBEN LYNN
金额：
$5.63万
依托单位：
--
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
项目状态：
已结题
起止时间：
2023-09-18 至 2024-09-17
关键词：
Adverse effectsAnimalsBehaviorBiologicalBiological AssayCellsChemicalsContractsDataDevelopmentDrug KineticsEnzymesExcretory functionHumanIn VitroMetabolismMethodsMolecularPermeabilityPharmaceutical PreparationsPhaseProcessPropertyServicesSolubilityStandardizationTestingTimeTissuesToxic effectabsorptionanalogbehavior predictionclinical candidatedesigndrug candidatedrug developmentdrug discoveryexperimental studyin vitro Assayin vivolead candidatenovelprogramssmall molecule
中文摘要
翻译
本合同的目的是使用分子方法测定两种新型化合物的体外ADMET（吸收、分布、代谢、排泄、毒性）。这些实验将有助于确定这些新化合物的药物样特性及其进一步开发的适用性。
英文摘要
The purpose of this contract is to determine in vitro ADMET (absorption, distribution, metabolism, excretion, toxicity) in two novel compounds using molecular methods. These experiments will help determine the drug-like properties of these novel compounds and their suitability for further development.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
CHARACTERIZATION OF SMALL-MOLECULE DRUG CANDIDATES USING STANDARDI
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批准号：10728466
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项目类别：
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资助金额：$15.72万
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财政年份：2022
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负责人：RALF GEIBEN LYNN
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依托单位：--
海外基金
