Novel silver nanoparticle coatings for the prevention of infection of biomedical implants and devices

该项目通过开发和评价抗菌银离子涂层，针对与植入物和生物医学器械（如导管、起搏器电极导线、膝关节和髋关节植入物）相关的感染。这种新的涂层方法更均匀和可重复，可应用于广泛的生物医学植入物和设备。将使用细胞和组织培养方法以及动物临床研究来测试新型涂层的抗菌有效性和安全性。

This project targets infections associated with implants and biomedical devices such as catheters, pacemaker leads, knee and hip implants, by the development and evaluation of coatings delivering antibacterial silver ions. The novel coating method is more uniform and reproducible and can be applied to a wide range of biomedical implants and devices. The novel coatings will be tested for antimicrobial effectiveness and safety using cell and tissue culture methods and animal clinical studies.