Nox isoforms and chemokine receptors as therapeutic targets in vascular disease and stroke

我是一名药理学家(研究药物及其工作原理的科学家)，试图寻找治疗心脏病和中风的新药。我试图了解导致高血压和高胆固醇患者动脉壁和中风后大脑中白细胞和自由基积聚的途径。然后，我将测试这些通路是否可以被新型化合物阻断，这些化合物可能最终会被开发成适合人类使用的药物。

I am a pharmacologist (a scientist who studies drugs and how they work) trying to find new drugs to treat heart attacks and strokes. I seek to understand the pathways that cause white blood cells and free radicals to accumulate in the walls of arteries in patients with high blood pressure and high cholesterol, and in the brain after stroke. I will then test whether these pathways can be blocked with novel chemical compounds that may eventually be developed into drugs suitable for use in humans.