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中文摘要
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描述(由申请人提供):申请部分资助将于2009年7月19-24日在罗德岛州纽波特的Salve Regina大学举行的第16届Gordon研究会议。生物钟在调节时间生理方面的重要性已经变得越来越明显,因此,人们致力于分析昼夜节律过程的潜在机制。人们认识到昼夜节律在人类健康和疾病中发挥的关键作用,再加上最近关于产生和调节昼夜节律系统的分子机制的里程碑式的发现,导致该领域的显著扩大。今天,时间生物学研究吸引了来自广泛学科的大量研究人员,包括神经科学、分子遗传学、光生物学、计算生物学和新陈代谢,以及睡眠医学、精神病学和肿瘤学。戈登时间生物学会议的目的是:1)为讨论和确定迅速发展的时间生物学领域的一般原则提供一个论坛。2)促进时间生物学各分支学科的研究人员之间的互动,从而增强整个研究领域的一致性。3)加强年轻和成熟研究人员之间的互动,从而保持高质量的时间生物学研究。4)通过聚集来自许多不同研究小组和国家的科学家,促进国家和国际合作。5)通过将使用模式生物的研究人员与研究昼夜节律研究的人类对象的研究人员聚集在一起,促进翻译研究。这次会议将汇集约150名科学家,包括来自不同国家、不同年龄段、不同性别的个人,并使用不同的研究模式,从而实现这些目标。该计划将侧重于关键研究领域的新的和正在出现的发展(见暂定计划)。按照非常成功的戈登会议形式,讲座将分8个上午和晚上进行,有充足的讨论时间。四人会议将允许参与者展示更多数据。特别注意实现性别平衡(见讨论领袖)和吸收来自不同学科的专家,以实现对我们科学前沿的广泛了解和对未来机会的洞察。公共卫生相关性:请求为将于2009年7月19日至7月24日在罗德岛州纽波特的Salve Regina大学举行的第16届戈登时间生物学研究会议提供部分支持。会议的目标是将一批不同的领先研究人员聚集在一起,开展一个专注于关键研究领域新出现的发展的项目,以增加互动,促进合作,并促进翻译研究。结果将对改善表现为睡眠、情感、认知、神经、代谢、内分泌和肿瘤疾病以及职业健康的功能障碍具有健康相关性。
英文摘要
DESCRIPTION (provided by applicant): Partial support is requested for the 16th Gordon Research Conference on Chronobiology, to be held on July 19-24, 2009 at Salve Regina University, Newport, Rhode Island. The significance of circadian clocks in regulating temporal physiology has become increasingly clear and as a result, much effort has been devoted to the analysis of the mechanisms underlying circadian processes. Recognition of the key role played by circadian rhythms in human health and disease, combined with recent landmark discoveries regarding the molecular mechanisms that both generate and regulate the circadian system, has led to a remarkable expansion of the field. Today, chronobiological research attracts a host of researchers from a broad range of disciplines, including neuroscience, molecular genetics, photobiology, computational biology, and metabolism, as well as sleep medicine, psychiatry, and oncology. The aims of the Gordon Conference on Chronobiology are: 1) To provide a forum for discussion and for identifying general principles in the rapidly expanding field of chronobiology. 2) To stimulate interactions among researchers working in the various sub-disciplines of chronobiology and thus enhance the coherence of the research field as a whole. 3) To intensify interactions between young and established researchers, and thus sustain high-quality chronobiological research. 4) To promote both national and international collaboration by bringing together scientists from many different research groups and countries. 5) To promote translational research by bringing together investigators employing model organisms with those studying human subjects in circadian research. The conference will achieve these goals by assembling approximately 150 scientists encompassing individuals from different countries, age groups, genders, and using different research models. The program will focus on new and emerging developments in key research areas (see Tentative Program). In accordance with the highly successful Gordon Conference format, lectures will be presented in 8 morning and evening sessions with ample time for discussion. Four poster sessions will allow participants to present additional data. Special attention has been given to achieving gender balance (see discussion leaders) and to including experts from very diverse disciplines to achieve a broadly-based understanding of the frontier of our science and insights as to future opportunities. PUBLIC HEALTH RELEVANCE: Partial support is requested for the 16th Gordon Research Conference on Chronobiology, to be held on July 19th-July 24th, 2009, at Salve Regina University, Newport, Rhode Island. Conference objectives are to bring together a diverse group of leading researchers for a program focused on new and emerging developments in key research areas, in order to increase interactions, promote collaboration, and promote translational research. Outcomes will have health relevance for ameliorating dysfunctions that manifest as sleep, affective, cognitive, neurological, metabolic, endocrine and oncological disorders and occupational health.
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Cell-type-specific analysis of the suprachiasmatic nucleus
  • 批准号:
    9425234
  • 项目类别:
  • 资助金额:
    $35.44万
  • 财政年份:
    2017
  • 负责人:
    JOSEPH S TAKAHASHI
  • 依托单位:
Cell-type-specific analysis of the suprachiasmatic nucleus
  • 批准号:
    10210449
  • 项目类别:
  • 资助金额:
    $35.44万
  • 财政年份:
    2017
  • 负责人:
    JOSEPH S TAKAHASHI
  • 依托单位:
Cell-type-specific analysis of the suprachiasmatic nucleus
  • 批准号:
    9750837
  • 项目类别:
  • 资助金额:
    $35.44万
  • 财政年份:
    2017
  • 负责人:
    JOSEPH S TAKAHASHI
  • 依托单位:
Molecular interactions of mammalian circadian clock proteins
  • 批准号:
    8692928
  • 项目类别:
  • 资助金额:
    $30.21万
  • 财政年份:
    2013
  • 负责人:
    JOSEPH S TAKAHASHI
  • 依托单位:
海外基金