Consensus Workshop to Address Kidney Health in High-Risk Neonatal Intensive Care Unit Graduates

慢性肾脏病（CKD）在需要在新生儿重症监护室接受护理的新生儿中很常见 （NICU），特别是早产儿、危重新生儿和患有先天性心脏病的新生儿。 对早产儿长期肾功能的研究显示， 青春期和成年期。CKD的负担将继续增加， 新生儿存活到成年期，并且存活阈值在妊娠22周之后继续降低。 尽管已知从NICU出院的新生儿存在CKD风险，但目前没有建议概述哪些患者 应监测CKD，应监测的时间，或应进行的检测类型 肾脏健康监测此外，我们对今后必要步骤的理解存在差距， 新生儿肾病学研究和临床护理的机会，这导致缺乏动力， 新生儿肾脏病学社区。为了填补这些知识空白，我们提出了“共识研讨会， 解决高风险新生儿重症监护病房毕业生的肾脏健康问题”，目的如下：1） 为三名高危新生儿制定NICU出院后肾脏健康监测的专家指导 2）确定新生儿肾病研究和临床护理的差距，重点关注肾脏健康和CKD 在NICU出院后，以及3）建立工作组，开始缩小新生儿肾脏病学的这些差距， 关注NICU出院后的肾脏健康和CKD。本次研讨会的成功举办将带来 制定建议，以帮助临床医生确定谁，何时以及如何评估肾脏 NICU毕业生的健康状况。这些建议不仅可以改善临床护理， 也将有助于改善我们进行研究的方式。我们还将确定研究和临床护理的优先事项， 新生儿肾脏病学，重点关注NICU毕业生的肾脏健康和CKD风险。最后，我们将开发 合作研究小组，以确定的新生儿肾脏病学优先领域为基础 在研讨会期间，并允许就如何解决这些差距进行对话。最终产品将是 建立研究基础设施，这将为向NIH提交拨款奠定基础。这项工作将 在研讨会期间完成，对于NIH未来的研究作为实用的临床研究至关重要 多中心协作工作需要对肾脏的最佳实践有共同的理解 健康监测。本次研讨会将汇集一个多元化的和有代表性的儿童和成人群体， 肾脏病学家、肾脏病学家、心脏病学家、重症监护医生、儿科医生、健康服务研究人员、患者和 家庭和宣传专家，以实现上述目标。此外，通过让受训者积极参与 制定后续指南，确定研究和临床护理差距， 通过与各工作组的合作，我们努力进一步发展新生儿肾脏病学领域的研究管道。

Chronic kidney disease (CKD) is common in neonates who require care in the Neonatal Intensive Care Unit (NICU), particularly in premature neonates, critically ill neonates, and those with congenital heart disease. Studies of long-term kidney function in children born prematurely show a threefold increase in CKD by adolescence and into adulthood. The burden of CKD will continue to increase as more extremely preterm neonates survive into adulthood and the threshold of viability continues to decrease beyond 22 weeks’ gestation. Despite the known CKD risk for neonates discharged from the NICU, no current recommendations outline who should be monitored for CKD, when they should be monitored, or what types of testing should be performed for kidney health monitoring. Furthermore, there is a gap in our understanding of the necessary next steps and opportunities in neonatal nephrology research and clinical care, which contributes to a lack of momentum in the neonatal nephrology community. To fill key these knowledge gaps, we propose the “Consensus Workshop to Address Kidney Health in High-Risk Neonatal Intensive Care Unit Graduates” with the following aims: 1) To develop expert-based guidance on kidney health monitoring after NICU discharge for three high-risk neonatal groups, 2) Identify gaps in neonatal nephrology research and clinical care, focusing on kidney health and CKD after NICU discharge, and 3) Develop working groups to begin to close these gaps in neonatal nephrology, focusing on kidney health and CKD after NICU discharge. Successful completion of this Workshop will result in the development of recommendations to assist clinicians in determining who, when, and how to evaluate kidney health in NICU graduates. These recommendations will not only allow for improvements in clinical care, but they will also help improve how we perform research. We will also identify research and clinical care priorities in neonatal nephrology, focusing on kidney health and CKD risk in NICU graduates. Finally, we will develop Collaborative Research Groups to build upon the prioritization areas in neonatal nephrology that are identified during the Workshop, and allow for conversations on how to address these gaps. The end product will be the establishment of research infrastructure, which will set the stage for grant submission to NIH. The work that will be accomplished during the workshop is essential to future research through NIH as pragmatic clinical studies and multicenter collaborative work requires a shared understanding of best practices when it comes to kidney health monitoring. This Workshop will bring together a diverse and representative group of pediatric and adult nephrologists, neonatologists, cardiologists, intensivists, pediatricians, health service researchers, patients and families, and advocacy experts to accomplish the above aims. Furthermore, by involving trainees actively in the development of follow-up guidelines, identification of research and clinical care gaps, and formation of collaborative working groups, we strive to further develop the research pipeline in the neonatal nephrology field.