Preclinical Pharmacology and Toxicology Studies

在临床前药理学和毒理学项目领域进行的研究是为了满足新药研究（IND）向FDA申请的要求。所有与研究药物的药理学、毒理学和安全性相关的技术报告都作为IND和研究药物手册的一部分提交给FDA。成功的IND申请允许DCP进行候选化学，植物和生物化学预防剂的临床试验，并作为临床前实验室结果与临床试验和原理证明研究之间的转化桥梁。

Studies conducted in this preclinical pharmacology and toxicology program area are designed to satisfy requirements for Investigational New Drug (IND) applications to the FDA. All technical reports related to the pharmacology, toxicology, and safety of investigational agents are submitted to the FDA as part of the IND and Investigational Drug Brochure. Successful IND filing allows DCP to conduct clinical trials of candidate chemical, botanical, and biological chemopreventive agents and serves as a translational bridge between preclinical laboratory results and clinical trials and proof of principle studies.