Enhancing Information Dissemination on Health Disparities Research: A Database

描述（由申请人提供）：加强关于健康差异的信息传播研究恢复法案NIH赠款的有限竞争：研究和研究基础设施“巨大的机会：（RC 2）RFA-OD-09-004本项目的目标是开发和提供一个复杂的关系数据库，其中包含关于健康差异的研究和其他相关工作的记录。该数据库被设想为所有健康差异工作的更新和可更新的概要，过去，现在和未来，由NIH和其他美国政府实体资助。这样一个数据库的存在将是一个布恩的研究人员，临床医生和政府机构，处理服务不足的人口和少数民族和任何群体遭受健康的差距。它还将协助政府资助机构确定哪些研究领域存在知识差距，需要额外的资金。这样一个数据库将满足迫切的需要。随着个性化医疗越来越接近现实，研究正在阐明许多基因在疾病病因学和治疗反应中的作用，确定哪些因素可能导致某些人群的疾病表现和反应差异，从而导致健康差异，这一点至关重要。为什么非裔美国人心脏病、癌症、脑血管疾病和糖尿病的死亡率高于白人的问题将在该数据库的内容中得到解决。为什么西班牙裔女性的非霍奇金淋巴瘤的发病率最高的所有少数群体？为什么一些少数群体更容易患糖尿病？这些是遗传影响，文化影响，环境影响，或三者的某种混合。希望这些问题的答案将存在于这个数据库中的研究中。而且，如果没有答案，政府机构将投资研究以找到答案。该数据库将为联邦政府、医学研究人员、临床医生以及最终为公众提供易于访问的信息。在为期两年的项目结束时，该数据库将移交给美国国立卫生研究院少数民族健康和健康差异国家中心。加强健康差异研究的信息传播PHS 398研究计划组成部分（SF 424（R&R）申请第5.5节）Spectrum Unlimited提议为国家健康差异研究协调中心开发基础设施，该中心将包括一个多方面的可搜索数据库，最初由NIH资助的关于健康差异的信息和研究，但最终会成为一个关于健康差异的研究汇编。我们打算以可供使用的格式完成本报告，并在补助期结束时将其全部退还给NCMHD。

DESCRIPTION (provided by applicant): Enhancing Information Dissemination on Health Disparities Research Recovery Act Limited Competition for NIH Grants: Research and Research Infrastructure "Grand Opportunities: (RC2) RFA-OD-09-004 The goal of this project is to develop and provide a complex relational database containing records on research and other related work on health disparities. The database is envisioned as an updated and updatable compendium of all health disparities work, past, present, and future, funded by the NIH and other U.S. government entities. The existence of such a database will be a boon to researchers, clinicians, and government agencies that deal with underserved populations and minorities and any groups that suffer from health disparities. It will also assist government funding agencies in determining which areas of research have knowledge gaps and need additional funding. Such a database will fill an urgent need. As personalized medicine is coming much closer to reality, and research is elucidating the roles of many genes in disease etiology and responses to therapy, determining what may yield differences in disease manifestation and response in some populations that may result in health disparities, is essential. Questions of why African Americans have higher death rates than whites from heart disease, cancer, cerebrovascular diseases and diabetes will be addressed in the contents of this database. Why do Hispanic women have the highest incidence rates of non-Hodgkin lymphoma of all minority groups? Why are some minority groups more prone to diabetes? Are these genetically influenced, culturally influenced, environmentally influenced, or some mixture of the three. The hope is that the answers to some of these questions will lie in research that will be included within this database. And, if there is no answer, the intention is that government agencies will invest in research to find the answers. This database will provide easily accessible information to the federal government, medical researchers, clinicians, and, eventually, the general public. At the end of the two-year project, the database will be turned over to the National Center on Minority Health and Health Disparities of the NIH. Enhancing Information Dissemination on Health Disparities Research PHS398 Research Plan Component (Section 5.5 of SF424 (R&R) Application) Spectrum Unlimited proposes to develop the infrastructure for a National Health Disparities Research Coordinating Center that will comprise a multi-faceted, searchable database, initially of information and studies funded by NIH on health disparities, but eventually to be a compendium of research on health disparities. We intend to complete this in a format to be ready for use and to be returned to NCMHD in total at the end of the grant period.