FOXJ1 EXPRESSION IN PULMONARY EPITHELIUM
FOXJ1 EXPRESSION IN PULMONARY EPITHELIUM
批准号:
7824118
负责人:
Steven Brody
金额:
$1.62万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-06-01 至 2011-08-31
中文摘要
通过与感觉纤毛相关的第二类基因,
是独立于Foxj1的。检验这一假说的具体目的将解决:(1)依赖Foxj1的基因
描述Foxj1激活运动组装和功能的机制,以及(2)Foxj1非依赖性
感觉性纤毛基因研究它们在运动纤毛组装和功能中的作用。完成拟议的
研究将提供有关哺乳动物纤毛发生调控的信息,并开辟新的途径
研究感觉蛋白在呼吸道上皮细胞中的进化作用。调查委员会的职能
纤毛细胞为研究呼吸道疾病的发生、分化和发病机制提供了新的思路。
项目说明第6页
英文摘要
by a second class of genes associated with sensory cilia, that
are Foxj1-independent. Specific Aims to test this hypothesis will address: (1) Foxj1-dependent genes to
characterize mechanisms of Foxj1 activation for motile assembly and function, and (2) Foxj1-independent
sensory cilia genes to investigate their roles in motile cilia assembly and function. Completion of the proposed
studies will provide information related to the regulation of mammalian ciliogenesis and open new avenues for
examining the evolving role of sensory proteins in airway epithelial cells. Investigation of functions of the
ciliated cell will provide new insights into development, differentiation and pathogenesis of airways diseases.
Project Description Page 6
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Molecular Imaging CCR2 Lung Inflammation and Fibrosis
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批准号:10343745
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项目类别:
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资助金额:$76.93万
-
财政年份:2021
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负责人:Steven Brody
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依托单位:
Molecular Imaging CCR2 Lung Inflammation and Fibrosis
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批准号:10543473
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项目类别:
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资助金额:$77.25万
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财政年份:2021
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负责人:Steven Brody
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依托单位:
Cellular and Molecular Features of Gene Mutations in Primary Ciliary Dyskinesia
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批准号:9898458
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项目类别:
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资助金额:$56.81万
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财政年份:2019
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负责人:Steven Brody
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依托单位:
Cellular and Molecular Features of Gene Mutations in Primary Ciliary Dyskinesia
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批准号:10378548
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项目类别:
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资助金额:$56.85万
-
财政年份:2019
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负责人:Steven Brody
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依托单位:
PET IMAGING CCR2 IN LUNG INFLAMMATION
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批准号:9090560
-
项目类别:
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资助金额:$64.93万
-
财政年份:2016
-
负责人:Steven Brody
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依托单位:
REGULATION OF MOTILE CILIA ASSEMBLY IN LUNG DISEASE
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批准号:8941243
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项目类别:
-
资助金额:$57.64万
-
财政年份:2015
-
负责人:Steven Brody
-
依托单位:
Regulation of Motile Cilia Assembly in Lung Disease
-
批准号:10608147
-
项目类别:
-
资助金额:$78.59万
-
财政年份:2015
-
负责人:Steven Brody
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依托单位:
Regulation of Motile Cilia Assembly in Lung Disease
-
批准号:9887501
-
项目类别:
-
资助金额:$78.69万
-
财政年份:2015
-
负责人:Steven Brody
-
依托单位:
ROLE OF MYB FOR AIRWAY EPITHELIAL CELL DIFFERENTIATION
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批准号:9268062
-
项目类别:
-
资助金额:$38.13万
-
财政年份:2015
-
负责人:Steven Brody
-
依托单位:
ROLE OF MYB FOR AIRWAY EPITHELIAL CELL DIFFERENTIATION
-
批准号:8885389
-
项目类别:
-
资助金额:$38.13万
-
财政年份:2015
-
负责人:Steven Brody
-
依托单位:
Regulation of Motile Cilia Assembly in Lung Disease
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批准号:10376783
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项目类别:
-
资助金额:$78.75万
-
财政年份:2015
-
负责人:Steven Brody
-
依托单位:
Bacteria-Epithelial Cell Cytoskeleton Interaction
-
批准号:6921030
-
项目类别:
-
资助金额:$34.43万
-
财政年份:2005
-
负责人:Steven Brody
-
依托单位:
Bacteria-Epithelial Cell Cytoskeleton Interaction
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批准号:7413584
-
项目类别:
-
资助金额:$32.64万
-
财政年份:2005
-
负责人:Steven Brody
-
依托单位:
Bacteria-Epithelial Cell Cytoskeleton Interaction
-
批准号:7096662
-
项目类别:
-
资助金额:$33.62万
-
财政年份:2005
-
负责人:Steven Brody
-
依托单位:
Bacteria-Epithelial Cell Cytoskeleton Interaction
-
批准号:7234082
-
项目类别:
-
资助金额:$32.64万
-
财政年份:2005
-
负责人:Steven Brody
-
依托单位:
MOLECULAR LINKS FOR CILIOGENESIS AND LEFT RIGHT AXIS
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批准号:6351605
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项目类别:
-
资助金额:$30.74万
-
财政年份:2000
-
负责人:Steven Brody
-
依托单位:
MOLECULAR LINKS FOR CILIOGENESIS AND LEFT RIGHT AXIS
-
批准号:6499039
-
项目类别:
-
资助金额:$31.61万
-
财政年份:2000
-
负责人:Steven Brody
-
依托单位:
MOLECULAR LINKS FOR CILIOGENESIS AND LEFT RIGHT AXIS
-
批准号:6629057
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项目类别:
-
资助金额:$32.55万
-
财政年份:2000
-
负责人:Steven Brody
-
依托单位:
MOLECULAR LINKS FOR CILIOGENESIS AND LEFT RIGHT AXIS
-
批准号:6039062
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项目类别:
-
资助金额:$30.03万
-
财政年份:2000
-
负责人:Steven Brody
-
依托单位:
MOLECULAR LINKS FOR CILIOGENESIS AND LEFT RIGHT AXIS
-
批准号:6697116
-
项目类别:
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资助金额:$33.52万
-
财政年份:2000
-
负责人:Steven Brody
-
依托单位:
海外基金