Emerging Infections Program-ARRA-317

这项建议的长期目标是发现、调查、控制和防止出现 传染性疾病。这些将通过在以下方面创建的新感染计划来实现 位于俄勒冈州的州公共卫生管理局将开展活跃的公共卫生疾病 监测；2)开展应用公共卫生流行病学和实验室活动；3)实施和 评估试点预防和干预项目。将在与其他合作伙伴的协作中开展活动 州卫生部门和联邦疾病控制与预防中心。 更具体地说，将对细菌病原体的侵入性感染进行积极监测， 包括A组和B组链球菌、肺炎链球菌、流感嗜血杆菌和奈瑟氏菌 脑膜炎和耐甲氧西林金黄色葡萄球菌；用于肠道和食源性感染 由各种细菌、病毒和原生动物引起；用于病毒性肝炎；用于呼吸道疾病，尤其是 医护人员肺炎和流感导致儿童住院；不明原因死亡 似乎是传染性的；对于克雅氏病来说。主动监控将包括 确定疾病风险高的人口群体和疾病发病率的趋势。 该计划将进行流行病学研究，以确定所列疾病的可改变的风险因素。 并评估疫苗计划和其他控制措施的有效性。它将会扩大 公共卫生调查暴发的能力，以确定各种病原体的传播途径。 它将扩大公共卫生实验室鉴定和分子流行病学分析的能力 细菌和病毒病原体。

The long-term objectives of thisproposal are to detect, investigate, control,and prevent emerging infectiousdiseases. These will be accomplishedthroughan Emerging Infections Program createdwithin the state public-health administrationin Oregon, which will 1) conductactive, public-healthdisease surveillance;2) conductapplied public-health epidemiologicand laboratoryactivities;and 3) implement and evaluate pilotprevention and intervention projects. Activitieswill be conductedin collaborationwith other state health departments and the federal Centers for Disease Controland Prevention. More specifically, active surveillancewill be conductedfor invasive infectionby bacterialpathogens, includinggroups A and B streptococci,Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis,and for methicillin-resistantStaphylococcusaureus; for entericand foodborne infections caused by various bacteria, viruses, and protozoa;for viral hepatitis;for respiratory illnesses,especially pneumonia in healthcare workers and influenza causing hospitalizationof children; for unexplaineddeaths that appear to be infectious;and for Creutzfeldt-Jakob disease. Active surveillancewill include the identificationof demographic groupsat high riskfor disease and trends in disease incidence. This program will conduct epidemiologic research to determine modifiable risk factors for diseases listed above and to evaluate the effectiveness of vaccine programs and other controlmeasures. It will expand public-healthcapacityfor investigationof outbreaksto identify means of transmissionof variouspathogens. It will expand public-healthlaboratory capacity for the identificationand molecular epidemiologicanalysisof bacterialand viral pathogens.