Molecular Basis of Gene Expression and Signal Processing

描述（由申请人提供）：来自密苏里大学三个系（生物化学、生物科学、分子微生物学和免疫学）和一个跨学科研究生项目（遗传学领域项目）的41名杰出研究人员提议继续发展分子和细胞生物学的跨学科项目。培训项目以生命科学中心为中心，这是一个校园内的新研究所，为MU校园内的跨学科研究和培训提供了一个框架。目前的培训项目由六个nigms资助的培训项目和一个膳食补充剂办公室资助的培训项目提供支持。本提案要求将政府间管理系统支助的职位增加到8个。在该计划中，培训将包括六个综合要素，包括(1)遗传学，分子，细胞和发育生物学以及职业道德的正式课程，(2)在选择导师之前在不同实验室进行轮转项目，(3)在选定导师的实验室进行论文研究，(4)学生研讨会和为同伴互动而设计的海报会议，(5)在同行评审的期刊上发表研究成果。(6)在国内和国际会议上发表年度报告。该培训计划由密苏里大学生命科学奖学金计划管理，该计划赞助跨学科研究生研究奖学金，全校范围内的研究活动，称为生命科学周，并协调研究生招聘，包括少数民族学生的招聘和保留。接受培训资助的受训者由培训资助教师提名，并由执行委员会根据他们的本科培训、研究生课程和研究项目的进展进行选择。目前的培训补助金对MU校园的跨学科研究生研究和培训产生了重大影响，并推动了校园对生命科学奖学金计划的投资增加。我们相信，NIGMS相对适度的投资将继续为MU校园的研究生研究和培训带来巨大的回报。

DESCRIPTION (provided by applicant): A group of 41 outstanding investigators from three departments (Biochemistry, Biological Sciences and Molecular Microbiology and Immunology) and one interdisciplinary graduate program (Genetics Area Program) at the University of Missouri propose to continue developing an interdisciplinary program in molecular and cellular biology. The training program is centered in the Life Sciences Center, a new institute on campus that provides a framework for interdisciplinary research and training on the MU campus. The current training program is supported by six NIGMS-funded traineeships and one traineeship funded by the Office of Dietary Supplements. An increase in the number of NIGMS-supported positions to eight is requested in the current proposal. In this program, training will consist of six integrated elements, including (1) formal courses in genetics, molecular, cellular and developmental biology and professional ethics, (2) rotation projects in different laboratories prior to selection of a mentor, (3) thesis research in the laboratory of a selected mentor (4) student seminars and poster sessions designed for peer-to-peer interactions, (5) publication of research findings in peer-reviewed journals, and (6) annual presentations at national and international meetings. This training program is administered by the Life Sciences Fellowship Program at the University of Missouri, which sponsors interdisciplinary graduate research fellowships, a campus-wide research event termed Life Sciences Week, and coordinates graduate student recruitment, including the recruitment and retention of minority students. The trainees selected for support on the training grant are nominated by the training grant faculty and selected by an executive committee on the basis of their undergraduate training, graduate coursework and progress in their research program. The current training grant has had a major impact on both interdisciplinary graduate research and training on the MU campus and has been the impetus for increased investment by the campus in the Life Sciences Fellowship program. We believe that a relatively modest investment by NIGMS will continue to pay large dividends in graduate research and training on the MU campus.