Mental Health Outcomes in Young Adults Previously Treated for Child Anxiety

描述（由申请人提供）：在青年时期患有焦虑症与成年后患心理障碍的可能性较高有关。治疗青少年焦虑症可能会减少以后生活中焦虑，抑郁和物质使用障碍的可能性。本研究旨在通过比较治疗完成15年后成功和失败治疗的参与者来评估与儿童焦虑治疗相关的长期结果。 在一项随机临床试验中，对118名被诊断患有焦虑症并被随机分配接受治疗的青年进行了抽样（Kendall等人，1997年）将应邀参加。受试者将在15年前随机接受治疗，并将参加一次为期半天的评估。评估将包括纸笔自我报告措施和诊断访谈，以评估自上次评估以来的焦虑水平，抑郁症状和物质使用情况。还将收集和评价自治疗以来有关功能障碍和生活事件的信息。 为了检验既往治疗结局对焦虑后遗症的影响，将进行Logistic和线性回归，以检查结局状态（治疗后诊断状态指示的成功/不成功）是否可预测自末次评价以来的成人焦虑、抑郁症状/障碍和随后的物质使用/滥用。将检查自我报告的症状和诊断状态。本研究将是第一个评估治疗青少年焦虑症对焦虑，抑郁和药物滥用的长期影响的研究，这些疾病经常出现在成年早期。 公共卫生相关性：本研究将是第一个评估治疗青少年焦虑症对焦虑，抑郁和药物滥用/滥用的长期影响的研究，这些疾病经常出现在年轻的成年期。从公共卫生的角度来看，这是很重要的，因为它将告知早期干预焦虑对疾病的负面后遗症是否有好处（例如，药物滥用/滥用，抑郁症）。关于焦虑干预的任何有利影响的知识将提供关于通过治疗原发性疾病来预防继发性疾病的重要见解。

DESCRIPTION (provided by applicant): Having an anxiety disorder in youth is associated with a higher likelihood of developing a psychological disorder in adulthood. Treating youth with anxiety disorders may reduce the likelihood of anxiety, depressive, and substance use disorders later in life. This study is designed to evaluate long-term outcomes associated with treatment for childhood anxiety by comparing successfully and unsuccessfully treated participants fifteen years after the completion of treatment. A sample of 118 youth who had been diagnosed with an anxiety disorder and who had been randomized to treatment in a randomized clinical trial (reported in Kendall et al., 1997) will be invited to participate. Participants will have been randomized to treatment 15 years prior and will participate in a half-day evaluation on one occasion. The evaluation will include paper-and- pencil self-report measures and a diagnostic interview conducted to assess for anxiety levels, depressive symptoms, and substance use since the last evaluation. Information regarding functional impairment and life events since therapy will also be gathered and evaluated. To test the effect of previous treatment outcome on the sequelae of anxiety, Logistic and linear regression will be conducted to examine whether outcome status (successful/unsuccessful as indicated by posttreatment diagnostic status) predicts adult anxiety, depressive symptoms/disorder and subsequent substance use/abuse since the time of the last evaluation. Both self-reported symptoms and diagnostic status will be examined. The present study will be the first to assess the long-term effects of treatment for an anxiety disorder in youth on anxiety, depression, and substance abuse through the period of young adulthood when these disorders are often seen. PUBLIC HEALTH RELEVANCE: The present study will be the first to assess the long-term effects of treatment for an anxiety disorder in youth on anxiety, depression, and substance misuse/abuse through the period of young adulthood when these disorders are often seen. This is important from a public health perspective because it will inform if there are advantages to early intervention of anxiety on negative sequelae of the disorder (e.g., substance misuse/abuse, depression) in adulthood. Knowledge about any advantageous effects of an anxiety intervention will provide important insight regarding prevention of secondary disorders by treating a primary disorder.