Optimising the therapeutic efficacy of protein-based drugs against lymph-resident diseases

由于缺乏针对疾病进展的淋巴部位的药物评估，淋巴疾病（如艾滋病毒和淋巴转移性癌症）的有效治疗受到限制。因此，改善药物进入淋巴的途径对改善这些疾病的治疗具有重大的潜力。因此，我们将探索一种新的方法来改善淋巴吸收和保留基于蛋白质的药物，使用一种有用的和广泛使用的生物相容性聚合物。

Effective treatments for lymphatic diseases (such as HIV and lymph-metastatic cancers) are limited by the lack of drug assess towards the lymphatic sites of disease progression. Improving the access of drugs into lymph therefore has the significant potential to improve the treatment of these illnesses. We will therefore explore a novel approach to improving the lymphatic uptake and retention of protein-based drugs using a useful and widely used biologically compatible polymer.