Administrative Core Management Plan

这三个研究项目将得到一个行政核心的支持，该核心将有助于协调项目之间化合物和数据的顺利交换，并促进与NIH科学和行政人员的接口。核心将由Kellar博士领导，他是整个项目的PI。执行委员会，由PI、三名项目负责人 分配到我们项目的美国国家卫生研究院和美国国立卫生研究院的科学人员将每年举行两次会议，审查科学进展，交换有关具体研究计划和设计的信息，并在认为可行的情况下调整优先事项。每年的两次执行委员会会议将计划于5月在乔治敦大学和10月或11月在杜克大学举行。在杜克的会议 将与一年一度的杜克尼古丁会议相吻合，以方便和经济。行政核心将为这些会议做出安排;因此，我们已经包括了适度的差旅预算，以允许Levin博士前往乔治敦，PI和项目负责人前往杜克（该差旅预算独立于每个研究项目的差旅预算， 这是为了参加国家科学会议并在会议上展示数据，如神经科学学会年会或SRNT会议）。除了执行委员会的两次年度会议外，行政核心将安排每月电话会议，以讨论进展情况、问题和/或新的想法。Eric Donny博士 （美国）匹兹堡），尼古丁自我管理专家，已同意担任项目2的顾问。与这些协商有关的费用已列入项目2的预算。 行政核心将建立一个数据存储中心，其中包括乔治敦大学药理学系的数据硬拷贝档案和电子版本数据库。所有三个项目都将把它们的数据发送给行政核心，乔治敦大学信息安全办公室（主任大卫史密斯先生）将帮助设计必要的安全安排，以保护所有机密信息。数据中心将由肖博士和Core的兼职研究助理管理。我们计划将数据输入到一个安全的、有密码保护的网络空间的中央数据库中。该NCDDDG的所有关键人员都可以通过密码访问数据中心。以这种方式保存的数据应该大大有助于项目的管理和论文的准备，用于出版，会议和向NIH提交的年度进展报告。

The three research projects will be supported by an Administrative Core that will help to coordinate the smooth exchange of compounds and data between the projects and facilitate the interface with NIH scientific and administrative personnel. The Core will be led by Dr. Kellar, the PI for the overall Program. An Executive Committee, composed of the PI, the three Project Leaders and NIH scientific personnel assigned to our program will meet twice each year to review scientific progress, exchange information about specific research plans and designs and, if deemed advisable, adjust priorities. The two Executive Committee meetings each year will be planned for Georgetown University in May and Duke University in October or November. The meeting at Duke will coincide with the annual Duke Nicotine meeting for convenience and economy. The administrative Core will make the arrangements for these meetings; therefore, we have included a modest travel budget to allow Dr. Levin to travel to Georgetown and for the PI and Project Leaders to travel to Duke (this travel budget is independent of the travel budget in each Research Project, which is for trips to attend and present data at national scientific meetings, such as the Annual Meeting of the Society for Neuroscience or for the SRNT meeting). In addition to the two annual meetings of the Executive Committee, the Administrative Core will arrange monthly telephone conferences for the Committee to discuss progress, problems, and/or new ideas. Dr. Eric Donny (U. Pittsburgh), an expert on nicotine self-administration, has agreed to serve as a consultant to Project 2. The costs associated with these consultations are included in the budget for Project 2. The Administrative Core will establish a data storage center that will encompass archives of hard copies of data and a database of electronic versions in the Department of Pharmacology, Georgetown University. All three projects will send their data to the Administrative Core, and the Georgetown University Information Security Office (Mr. David Smith, Director) will help design the necessary security arrangements to protect all confidential information. The data center will be managed by Dr. Xiao and a part-time research assistant in the Core. We plan to enter the data into a central database on a secure, password-protected web space. All key personnel of this NCDDDG will have access to the data center via password. The data maintained in this way should help greatly in the management of the program and in the preparation of papers for publication, presentations for meetings and the annual progress reports to NIH.