CCTN - CLINICAL EVALUATION OF LONG ACTING REVERSIBLE CONTRACEPTIVES

LARC方法包括宫内节育器、植入物或长效阴道环。 LARC方法比每日、每周或每月的产品更有效，因为它们不太容易出现用户错误。 宫内节育器和植入物的有效率在典型使用中处于最高水平（>99%有效率）。 开发新的LARC方法是CDDB的高度优先事项。 LARC方法，含铜宫内节育器是唯一高效的可逆方法，不涉及激素的管理，不会导致不规则或计划外出血模式的妇女。 这些特性使铜宫内节育器和理想的方法，为妇女谁不希望采取或不能采取激素避孕方法。 含有合成雌激素和炔雌醇的产品与BTE的剂量依赖性增加有关。 铜宫内节育器不会增加静脉血栓栓塞的风险，如肥胖妇女，孕妇和莱顿因子V的妇女。一些研究的初步数据表明，较新的铜宫内节育器可能与较低的严重出血和/或痉挛的发生率有关，一些装置可能具有较少的插入疼痛。

LARC methods include IUDs, implants, or long acting vaginal rings. LARC methods are more effective than daily, weekly or monthly products because they are less prone to user error. IUDs and implants have an effectiveness rate that is in the top tier for typical use (>99% effective). Development of new LARC methods is a high priority for the CDDB. LARC methods, copper-containing IUDs are the only highly effective reversible methods that do not involve administration of hormones and do not cause irregular or unscheduled bleeding pattern in women. These properties make a copper IUD and ideal method for women who do not wish to take or cannot take hormonal contraceptive methods. Products containing the synthetic estrogen and ethinyl estradiol have been associated with a dose-dependent increase in BTE. Copper IUDs do not increase risk of VTE, such as obese women, pregnant women and women with Leiden Factor V. Preliminary data from some studies indicate that newer copper IUDs may be associated with a lower incidence of heavy bleeding and/or cramping and some devices may have less pain with insertion.