Imaging Core

组织学和成像核心将提供技术专长，培训， 用于组织处理和生物样本分析的最先进仪器，包括 共聚焦显微镜和体视学。在之前提交的文件中，我们没有组织学主任 和成像核心，而是建议招募一名高级科学家谁可以领导这个核心。我们有 在这次招募工作中取得了成功，增加了杰弗里·博夫博士，一位疼痛研究员， 主要集中在研究炎症如何影响初级传入伤害感受神经元。博夫博士 在神经和肌肉骨骼的组织学、图像采集、组织形态学方面具有丰富的经验 结构和免疫荧光形态测定法。他发表了大量的手稿， 和免疫组织学方法，以及使用电子显微镜。Bove博士还开发了 使用体视学和非体视学方法的免疫定量方法。另外我们有 招募了威利斯博士，他是COBRE项目的负责人，在共聚焦和电子显微镜方面具有专长， 组织学和成像核心主任将为研究者提供最佳方法， 解决他们的问题，提供方法和仪器方面的培训，并监督核心 经理/技术员。

The Histology and Imaging Core will provide technical expertise, training, and state-of-the-art instrumentation for the processing of tissue and the analysis of biological samples, including confocal microscopy and stereology. In the previous submission, we did not have a Director for the Histology and Imaging Core and instead proposed to recruit a senior level scientist who could lead this Core. We have been successful in this recruitment effort with the addition of Dr Geoffrey Bove, a pain researcher with a primary focus on examining how inflammation affects primary afferent nociceptive neurons. Dr Bove has extensive experience in histology, image acquisition, histomorphology of neural and musculoskeletal structures, and immunofluorescent morphometry. He has published numerous manuscripts using histological and immunohistological methods, as well as using electron microscopy. Dr Bove has also developed immunoquantification methods using stereological and non-stereologicat approaches. In addition, we have recruited Dr Willis, a COBRE Project Leader with expertise in confocal and electron microscopy who will serve as co-Director The Histology and Imaging Core Directors will advise investigators on the best approach to address their questions, provide training in methodology and instrumentation, and to supervise the Core manager/technician.