Photoprotection by vitamin D and analogs

迄今为止的发现和提出的研究表明，维生素D化合物在皮肤中具有保护皮肤免受阳光伤害的内在作用。由于阳光照射，皮肤中维生素D化合物的浓度会增加，这可能会提供防止进一步紫外线伤害的保护，就像皮肤外层色素沉着增加和厚度增加一样。此外，这些研究旨在测试对血清钙影响最小的维生素D化合物是否可以与防晒霜或润肤霜一起局部使用，以增加防晒作用。由于澳大利亚是世界上皮肤癌发病率最高的国家，这将具有重大的健康和经济价值。

The discoveries made to date and the proposed studies point to an intrinsic role for vitamin D compounds in skin in providing protection from sun damage. As a result of sun exposure, increased concentrations of vitamin D compounds in skin will be generated and this is likely to provide protection against further UV damage, in much the same way as increased pigmentation and increased thickness of the outer layer of skin. Furthermore, the studies are designed to test whether vitamin D compounds which have minimal effects on serum calcium, could nevertheless be used topically in association with a sunscreen or moisturizer to add to sun protection. As Australia has the highest skin cancer rates in the world, this would be of significant health and economic value.