Priming the maternal immune response to resist inflammatory disorders of pregnancy

先兆子痫和早产是每年影响1500万怀孕的常见疾病。一个潜在的原因是母亲的免疫反应，这可能会对胎儿产生不利的反应，引起炎症反应。该项目旨在寻找在受孕前就开始加强母体免疫系统的方法。这项工作将提供见解，为有意向的父母提供建议，并将为开发新的治疗方案提供信息，以保护易感妇女。

Preeclampsia and preterm birth are common conditions affecting >15 million pregnancies annually. An underlying cause is the mother’s immune response, which can react adversely to the fetus causing an inflammatory reaction. This project seeks to find ways to strengthen the maternal immune system beginning before conception. The work will provide insights upon which to advise intending parents and will inform development of new treatments options to protect susceptible women.