Amnion cell therapy for acute and chronic stroke

我们正在研究人羊膜上皮细胞（AECs）作为中风的新疗法。在这里，如果我们发现AECs的保护作用不受“凝块破坏”药物的影响，我们将扩大AECs的计划II期试验，包括接受过凝块溶解治疗的患者。此外，由于我们怀疑aec通过释放被称为“外泌体”的纳米颗粒来发挥其作用，我们将测试静脉注射或鼻内注射的外泌体是否具有类似的保护作用。

We are studying human amnion epithelial cells (AECs) as a new therapy for stroke. Here if we find the protective effects of AECs are unaffected by a 'clot-buster' drug,we will broaden our planned Phase II trial of AECs to include patients that have received clot lysis therapy. Further, as we suspect that AECs exert their effects via release of nanoparticles called 'exosomes', we will test whether exosomes given intravenously or intranasally are similarly protective.