Reducing the mortality gap for people with schizophrenia
Reducing the mortality gap for people with schizophrenia
批准号:
nhmrc : 1194635
负责人:
金额:
$123.11万
依托单位国家:
澳大利亚
项目类别:
Investigator Grants
财政年份:
2021
资助国家:
澳大利亚
项目状态:
未结题
起止时间:
2021-01-01 至 2025-12-31
中文摘要
精神分裂症患者比一般人早死16年,主要是由于糖尿病和心脏病等可避免的疾病。这项研究旨在对1型精神分裂症患者进行临床试验。现有的糖尿病药物(二甲双胍),以防止最初的体重增加由于抗精神病药物和2。一种新的糖尿病药物(艾塞那肽),可以帮助那些使用二甲双胍减肥效果不佳的人。
英文摘要
People with schizophrenia die >16 years earlier than the general population, mostly due to avoidable diseases such as diabetes and heart disease. This research aims to conduct clinical trials among people with schizophrenia of 1. an existing diabetes medication (metformin) to prevent initial weight gain due to antipsychotic medications and 2. a novel diabetes medication (exenatide) to help people who don’t have adequate weight loss with metformin.
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