Deciphering the Thermal Acclimation of Mitochondrial Respiration

植物在预先暴露于亚致死温度升高/降低后，适应极端温度。最近的研究表明，氧化磷酸化和三羧酸(TCA)循环的蛋白质是动态的，其丰度随着温度的变化而变化。利用尖端的蛋白质质谱学方法，该项目试图更好地了解线粒体呼吸作用以及三磷酸腺苷(ATP)的产生是如何在温度变化期间保持的。独一无二的是，该项目将在模式植物拟南芥和小麦中研究这一点，并结合组织、环境诱导和基因变异，以揭示对这一主要线粒体过程的热适应的新理解。

Plants acclimate to the extremes of temperature following a pre-exposure to a sub-lethal increase/decrease in temperature. Recent research has revealed that proteins of oxidative phosphorylation and the tricarboxylic acid (TCA) cycle are dynamic and change their abundance in response to temperature change. Harnessing a cutting edge protein mass spectrometry approach, this project seeks to better understand how mitochondrial respiration and hence adenosine triphosphate (ATP) production is maintained during temperature change. Uniquely this project will examine this in both the model plant Arabidopsis and wheat and combine both tissue, environment-induced and genotype variation to reveal a new understanding of the thermal acclimation of this major mitochondrial process.