An integrated omics approach to discover key mediators of tissue specificity in disease
An integrated omics approach to discover key mediators of tissue specificity in disease
批准号:
nhmrc : GNT1159594
负责人:
金额:
$61.56万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2019
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2019-01-01 至 --
中文摘要
线粒体功能失调导致多种多样的多系统人类病理,往往导致严重的、进行性和致命的疾病,而这些疾病没有有效的治疗方法。该项目将使用重要的线粒体疾病新模型来检查这些疾病的发病,进展和病理生理学-揭示组织特异性效应的原因,并为未来的治疗提供基础。
英文摘要
Dysfunctional mitochondria cause a diverse group of multi-system human pathologies that often result in severe, progressive and lethal diseases for which there are no effective treatments. This project will use important new models of mitochondrial disease to examine the onset, progression and pathophysiology of these disorders – revealing the reasons for the tissue-specific effects and providing a basis for future treatments.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
海外基金