An investigation into metabolic competition between host and pathogen in infection

先进的医学治疗伴随着危及生命的微生物感染的高风险，而日益增加的抗微生物药物耐药性要求创新的治疗策略。在这个项目中，我们将把代谢调节描述为感染的一种新的治疗靶点，重点是人类真菌病原体白色念珠菌，它导致医院感染，死亡率为40%。我们的研究结果将广泛适用于设计针对传染病的改进疗法。

Advanced medical treatments come with a high risk of life-threatening microbial infections, and rising antimicrobial drug resistance demands innovative therapeutic strategies. In this project, we will characterize metabolic regulation as a novel therapeutic target in infection, focusing on the human fungal pathogen Candida albicans that causes hospital infections with 40% mortality. Our outcomes will be broadly relevant to designing improved therapies against infectious diseases.