The effect of titanium surface modification on the immuno-regulation of osseointegration.
The effect of titanium surface modification on the immuno-regulation of osseointegration.
批准号:
nhmrc : 1036625
负责人:
Dr Stephen Hamlet
金额:
$20.59万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Early Career Fellowships
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2016-12-31
中文摘要
钛种植体是牙科和骨科的一种公认的治疗方式。该项目将确定在种植体与骨结合的过程中,种植体表面修饰如何调节炎症反应和干细胞随后的分化。因此,对相关分子机制的识别将为进一步加强骨整合过程和改善临床结果提供新的方法。
英文摘要
Titanium implants are an established treatment modality in both dentistry and orthopaedics. This project will determine how implant surface modification can modulate the inflammatory response and subsequent differentiation of stem cells involved in the process of integrating the implant with bone i.e. osseointegration. The identification of the molecular mechanisms involved will thus provide leads for novel ways to further to enhance the osseointegration process and improve clinical outcomes.
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