Australia Fellowship

Mackay教授通过这项澳大利亚奖学金，提出通过探索这些关于炎症和饮食和胃肠道微生物群作用的激进新思想，获得免疫反应的新知识。此外，他希望通过整合新的和强大的技术和方法，为生物疗法的产生开发新的治疗人类疾病的方法。最后，基因工程小鼠将是这一过程的关键，并将使新一代药物的发现成为可能，这在几年前是不可能的。澳大利亚研究金将利用相当多的跨学科互动，在医学研究方面产生强有力的新方向。例如，有相当多的证据，但对免疫系统是如何被代谢调节的，或者干细胞在与炎症相关的组织重塑中的作用，或者免疫系统与癌症之间微妙的相互作用，人们知之甚少。

Prof Mackay, through this Australia Fellowship, proposes to gain new knowledge on immune responses, by exploring these radical new ideas on inflammation and the role of diet and gastro-intestinal microflora. In addition, he hopes to develop new treatments for human diseases, by integrating new and powerful technologies and approaches for the generation of bio-therapeutics. Finally, genetically engineered mice will be pivotal in this process, and will enable the discovery of a new generation of medicines not possible a couple of years ago. The Australia Fellowship will draw on considerable cross-discipline interactions, to produce powerful new directions in medical research. For instance, there is considerable evidence, but poor understanding, of how the immune system is regulated by metabolism or the role of stem cells in tissue remodelling associated with inflammation, or the delicate interplay between the immune system and cancers.