Imaging system for DNA, RNA and proteins

所要求的设备是一种最先进的文件系统，可以满足CIHR或NSERC运营拨款支持的研究项目的迫切需求。除了6名调查员及其研究小组外，该部所有研究小组都将获得这些设备。包括研究生、博士后、技术人员和研究助理在内的40多人将常规使用这种设备。此外，每年超过25人的几名本科生在我们的实验室进行研究，作为他们在微生物学和免疫学本科学习的一部分。作为文件系统本身，该设备节省了时间，并在各种应用中增加了敏感性，无论是放射性的还是非放射性的。它还可以更容易地用更安全的非放射性替代品取代基于放射性同位素的方法。除了文件本身，该设备还允许对与我们各自的研究计划相关的各种应用程序的结果进行量化分析。微生物学和免疫学中细胞和分子生物学方法的发展要求对结果进行精确和可重复的定量分析，以便产生可靠的结论。我们的成员定期发表文章的顶级科学期刊经常要求这种方法，而所要求的设备可能是此类应用中最广泛接受的。因此，购买这种设备将极大地提高我们由运营拨款支持的研究的生产率，包括8种不同的、目前正在进行的NSERC支持的研究拨款。

The equipment requested is a state-of-the-art documentation system that meets urgent needs for research programs supported by operating grants from the CIHR or the NSERC. In addition to the 6 investigators and their research teams, the equipment will be available to all research teams of the department. Over 40 people, including graduate students, postdocs, technicians and research assistants will be using this equipment on a routine basis. In addition, several undergraduate students, more than 25 every year, are performing research in our laboratories as part of their undergraduate studies in microbiology and immunology. As a documentation system per se, the equipment saves time and gives added senstivity in various applications, radioactive and nonradioactive alike. It also allows easier replacement of radioisotope-based approaches by safer nonradioactive alternatives. In addition to documentation per se, the equipment allows quantitative analysis of the results in various applications pertinent to our respective research programs. Development of cellular and molecular biology approaches in microbiology and immunology requests precise and reproductible quantitative analysis of results, in order to generate solid conclusions. Such approaches are routinely requested by the top scientific journals in which our members are regularly publishing, and the requested equipment is probably the most widely accepted in such applications. Acquisition of this equipment will thus considerably improve the productivity of our research supported by operating grants, including 8 different currently active NSERC-supported research grants.