Brain Pathways Underlying Vulnerability to Drug Relapse

吸毒成瘾是澳大利亚社会的主要健康和社会负担。一旦成瘾，预防复发是成功治疗的最大障碍。不幸的是，治疗复发的有效药物选择不足。通过使用一个准确反映人类吸毒情况的复发动物模型，拟议的项目旨在促进我们对成瘾背后的大脑机制的理解。

Addiction to drugs is a major health and social burden for Australian society. Once addiction is established, prevention of relapse is the most significant obstacle to successful treatment. Unfortunately, efficacious pharmaceutical options to treat relapse are lacking. By employing an animal model of relapse that accurately reflects drug taking in humans the proposed project aims to advance our understanding of the brain mechanism underlying addiction.