Central aortic blood pressure in children: establishing a gold standard non-invasive assessment of cardiovascular risk

评估心血管疾病早期风险的最佳方法是测量心脏附近的血压（中心压），但现有用于成人的仪器在儿童中并不准确。我们将开发一种针对儿童的方法，并将其应用于对全澳大利亚2000名儿童的综合健康研究中，研究早期心血管风险。我们还将调查为什么患有先天性心脏病的儿童经常在年轻时患上“老年人”心脏病。

The best way of assessing early risk of cardiovascular disease involves measuring blood pressure near the heart (central pressure), but existing devices used in adults for this purpose are inaccurate in children. We will develop a children-specific method and apply it to study early cardiovascular risk in a comprehensive health study of 2000 children Australia-wide. We will also investigate why children with congenital heart disease frequently develop ‘older-adult’ heart disease at a young age.