Centrosome overduplication contributes to tumorigenesis
Centrosome overduplication contributes to tumorigenesis
批准号:
nhmrc : 631559
负责人:
Dr Rose Boutros
金额:
$33.01万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2012-12-31
中文摘要
癌症可以简单地认为是一种细胞生长和分裂的疾病。为了改进目前的治疗机制并确定新的治疗机制,需要充分了解控制细胞增殖的潜在机制。通过定义这些调控机制,可以进一步确定当前化疗药物的靶点并确定新的靶点。这将导致有针对性地开发可用于抗癌的新型药物。
英文摘要
Cancer can be simplistically thought of as a disease of cell growth and division. In order to improve current treatment regimes and identify new ones, the underlying mechanisms controlling cell proliferation need to be fully understood. By defining these regulatory mechanisms, targets for current chemotherapeutic agents can be further characterised and new ones identified. This will lead to the targeted developments of new classes of drugs which can be used in the fight against cancer.
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会议论文
Identification and functional analyses of novel post-translational modifications of CDC25B.
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批准号:nhmrc : 336704
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项目类别:Early Career Fellowships
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资助金额:$23.0万
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财政年份:2006
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负责人:Dr Rose Boutros
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依托单位:
海外基金