Characterisation of a newly-discovered, virulence-associated, protein secretion system of enteropathogenic E. coli

细菌的细胞壁是它们产生的任何蛋白质出口的屏障。我们最近发现了一个蛋白分泌系统，它能使引起大肠杆菌的菌株致病。大肠杆菌需要引起疾病。本研究的目的是了解这个分泌系统，并发现它是如何工作的，它分泌什么。从这项研究中获得的知识将为E。大肠杆菌引起疾病，并可能揭示新的方法来治疗和预防这种细菌的感染。

The cell walls of bacteria act as a barrier to the export of any proteins they produce. We recently discovered a protein secretion system, which diarrhoea-causing strains of E. coli require to cause disease. The aim of this study is to characterise this secretory system, and discover how it functions and what it secretes. The knowledge obtained from this research will shed new light on how E. coli causes disease and could reveal novel methods to treat and prevent infections with this bacterium.