Bioreactors for bioprocessing research

倡导者最近与NH的达特茅斯学院和一个工业合作伙伴合作开展了一项重大研究工作，目的是开发具有成本效益的纤维素生物质的生物转化，如用于生产乙醇的草和木材。目前有三名赖尔森的研究生参与了该项目，至少还有两名学生将于2008年9月加入该团队。目前的项目涉及与NH达特茅斯学院的李·林德博士和一个工业赞助商的密切合作。一名学生在达特茅斯学院度过了2007年的暑假，很明显，除了我们对合作的生态学和显微镜贡献外，我们还需要在瑞尔森进行恒化器实验；此外，我们还需要促进实验室间的比较，并避免延误对我们的微生物协会的评估。因此，我们的合作伙伴为我们的实验室提供了两个新的恒化器生物反应器，分别需要在2008年9月和2009年9月之前归还。本意见书请求支持购买这些反应堆的更换设备。来自瑞尔森大学至少两名同事和多伦多大学至少一名合作者的学生也将从这一系统中受益。虽然我们实验室对设备的主要需求是进行纤维素分解厌氧微生物群落的动力学研究(至少需要两个恒化器才能进行重复实验)，但我们经常需要这样的设备进行基础研究，以比较生物膜(附着细胞)和浮游细胞的表型。后者是我们组另外两名研究生的研究重点，而另一名学生将在2008年加入他们，作为最近与麦克马斯特大学和加拿大环境部的合作者合作的NSERC战略项目的一部分。我们系在环境科学方面经历了显著的增长，最近(2006/2007)和未来(2008)被任命为环境微生物学；随着2006年秋季引入的分子科学研究生课程，对恒化器生物反应器的需求越来越大。

The proponent has recently embarked on a major research effort in collaboration with Dartmouth College, NH and an industrial partner with the objective to develop cost effective bioconversion of cellulosic biomass such as grass and wood for ethanol production. There are currently three Ryerson-based graduate students involved in the project and at least two more will join the team in September 2008. The current project involves a strong collaboration with Dr. Lee Lynd at Dartmouth College, NH and an industrial sponsor. One student spent the summer of 2007 at Dartmouth College, and it became clear that we need to perform chemostat experiments at Ryerson in addition to our ecology and microscopy contribution to the collaboration; among others to facilitate inter-laboratory comparisons and to avoid delays in evaluating our microbial consortia. Our partners therefore made two new chemostat bioreactors available for our laboratory, which need to be returned by September 2008 and 2009, respectively. This submission requests support to purchase replacements for these reactors. Students from at least two colleagues at Ryerson and at least one collaborator from University of Toronto will also benefit from this system. Although the primary need for the equipment in our laboratory is to conduct kinetic studies of cellulolytic anaerobic microbial communities (at least two chemostats are needed to allow replicate experiments), we regularly need such equipment for our fundamental studies to compare the biofilm (attached cells) phenotype with their planktonic counterparts. The latter is the research focus of two other graduate students in our group, while another student will join them in 2008 as part of a recently-funded NSERC Strategic project in partnership with collaborators at McMaster University and Environment Canada.   Our department experienced notable growth in environmental sciences, with two recent (2006/2007) and one future (2008) appointment in environmental microbiology; together with the Molecular Sciences graduate program introduced in fall 2006 there is a growing need for chemostat bioreactors.